Retinol serum

This advanced formula has a phenomenally restorative influence on the many layers of the skin.

Acne:
Retinol improves and corrects the DNA communication between the cells to prevent the cells from clumping and sticking together. Retinol will also reduce the production of sebum and will assist in increasing exfoliation and unclogging of pores. Retinol will reduce inflammation that contributes to the formation of acne.

Pigmentation:
Tyrosinase inhibitor - Retinol inhibits the enzymes responsible for pigmentation.
Melanosome transfer inhibitor - DermExcel Retinol serum also includes Niacinamide that will inhibit pigment transfer to skin cells.
Keratolytic - Retinol will also accelerate the cell turnover to such an extent that it outpaces melanin production.

Aging:
Prevention: Retinol focuses on preventing wrinkle or aging formation on a cellular level by preventing the degradation of collagen and elastin.
Correction: Retinol and Niacinamide stimulate the production of collagen.
This formula will also reduce inflammation, which plays a significant role in degrading collagen and elastin within the skin.

Active ingredients

Full ingredient list
Aqua, Niacinamide, Acetyl Hexapeptide-8 & Caprylyl Glycol, Dimethyl Isosorbide & Hydroxypinacolone Retinoate, Glycerin, Hydroxypropyl Cyclodextrin & Palmitoyl Tripeptide-38, Sodium Acrylates Copolymer & Lecithin, Phenoxyethanol & Ethylhexylglycerin, Acrylates copolymer, Glycerin,  C14-22 Alkane, Pentaerythrityl Tetra-Di-t-Butyl Hydroxyhydrocinnamate

• Aging and sun-damaged skin
• Hyperpigmentation
• Dry and dehydrated skin
• Rosacea
• Acne/breakouts and congested pores

Apply in the morning and/or evening on cleansed skin before any other product.

Follow these 3 tips to get the most out of your serum.

1. Cleanse well

The active ingredients in skin serums will stick to dirt and dead skin, so for maximum absorption, be sure to wash your face properly before applying.

2. Apply to damp skin

Moist skin is more permeable than dry skin, so apply serum to damp skin after cleansing for quick, deep absorption. Press serum into the skin with an open palm instead of fingertips to release active ingredients.

3. Less is more 

Serums are super concentrated. Use just 1-2 pumps or a little smaller than a pea-size amount. 

Women want to look their best at this important time in their lives, and therefore it's important to determine which products and ingredients are safe to use during pregnancy.

Except for the two prescription molecules, hydroquinone (which has a relatively high systemic absorption rate) and tretinoin (for which the evidence is limited and controversial), skincare products act locally and produce minimal systemic levels. In most cases, women can deal with these cosmetically unappealing skin conditions without compromising the safety of their unborn children.

No DermExcel™ product contains hydroquinone or tretinoin. These active ingredients are only available by prescription from a medical doctor.

DermExcel™ Retinol serum contains an active ingredient very similar to tretinoin. We, therefore, advise customers to discontinue the use of Retinol serum until after pregnancy.

   FAQ's   

1. Why should I stop using Retinol if it doesn't contain one of the above prescription molecules that should be avoided during pregnancy?

Even though no evidence suggests that the molecule in our Retinol serum should be avoided during pregnancy, this particular active ingredient is an ester of the prescription molecule retinoic acid; therefore, our ethical and legal obligation is to be overly cautious. 

Discuss the use of topical Retinol usage during pregnancy with your gynecologist. They will be the best source of information regarding the safety risks. 

3. How long before I fall pregnant should I stop using Retinol serum?

As soon as you find out you are pregnant. We only advise you to stop using Retinol serum as a precaution. 

4. May I use the Retinol serum while breastfeeding?

Yes, it is safe to use the DermExcel Retinol serum while breastfeeding.  

• Because tretinoin (the prescription molecule, remember, our Retinol is an ester of the prescription molecule) is poorly absorbed after topical application. It is considered a low risk to the nursing infant. 
• Ref: Drugs and Lactation Database (Lactmed)
• Blood concentrations measured 2-48 hours following application are essentially zero. Absorption of Retin-A (Tretinoin) via topical sources is reported to be minimal, and breastmilk would likely be minimal to none.
• Ref: Dr. Thomas Hale, Medications and Mother's Milk
• Vitamin A and, presumably, tretinoin (all-trans-retinoic acid) are natural constituents of human milk. There are no data on the amount of all-trans retinoic acid excreted into milk after topical use. Although other retinoids are excreted (see Vitamin A), the minimal absorption after topical application of tretinoin probably precludes the detection of clinically significant amounts in breast milk from this source. Thus, the use of tretinoin while breastfeeding does not appear to represent a significant risk to a nursing infant.
• Ref: Drugs in Pregnancy and Lactation: Gerald Briggs, pharmacologist at Washington State University College of Pharmacy.

Please click here to learn more about why you need DermExcel Retinol serum in your regimen and why the DermExcel Retinol serum is superior to others. 

Click here to be directed to the comprehensive clinical trials page.