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DermExcel™ | Excelerate
DermExcel™ | Excelerate
DermExcel™ | Excelerate
DermExcel™ | Excelerate
DermExcel™ | Excelerate
Excelerate Excelerate Excelerate Excelerate
DermExcel™

Excelerate

Sale price R 202.00
4.9 / 5.0 from 467 reviews

Pay interest-free installments from R 50.50 with various payment gateways selected at checkout.

Size:

Size
Strength:

Strength
↓ Sebum

↓ Sebum

Unclog Pores

Unclog Pores

Ingrown hair

Ingrown hair

Anti-Acne

Anti-Acne

↓ inflammation

↓ inflammation

A high-potency Salicylic acid treatment available in two strengths – 15% and 30%. This efficacious formulation is designed to systematically counteract acne formation by addressing the critical stages of acne development: comedones, bacteria, and inflammation. It maintains a balance in oil secretion, and its unique keratolytic action accelerates the turnover of skin cells, fostering flaking on the epidermis and inside the pores. This process aids in unclogging pores, a fundamental step in acne management.

The powerful antibacterial properties of Salicylic acid in Excelerate combat acne-causing bacteria, inhibiting their growth and reducing their presence on the skin. This targeted action helps to clear existing acne lesions and prevent the formation of new ones, promoting a clearer complexion. It also down-regulates the inflammatory response associated with acne. Reducing redness and swelling helps soothe the visible signs of inflammation, relieving troubled skin.

Excelerate's dual strengths offer flexibility in treatment options, allowing individuals to choose the appropriate concentration based on their specific needs and skin sensitivity. The 15% strength provides a gentle yet effective approach, while the 30% strength offers a more intensive treatment for stubborn or severe acne.

Excelerate should be used as directed and is recommended for individuals seeking a targeted solution to acne concerns. As with any acne treatment, it is advisable to consult with a healthcare professional or dermatologist to determine the most suitable strength and usage guidelines for your individual skin type and condition.

Salicylic acid | 15%

Salicylic acid | 15%

Salicylic acid, a renowned beta hydroxy acid (BHA), is a cornerstone in dermatology and skincare due to its exceptional keratolytic and comedolytic properties. Its unique ability to penetrate oil-laden hair follicle pores makes it particularly effective in treating acne-prone and oily skin types.

Salicylic acid dissolves skin debris (sebum and dead skin cells) that clogs pores and causes acne. It's a mild antibacterial and powerful anti-inflammatory agent that helps reduce the redness and swelling associated with breakouts.

What sets salicylic acid apart in dermatological treatments is its ability to exfoliate the skin, not just on the surface but within the pores themselves. This is due to its oil-soluble nature, which allows it to penetrate deep into the pores and dissolve the keratin plugs that lead to blackheads and whiteheads.

Furthermore, salicylic acid also has the capacity to adjust the pH of the skin, creating an environment less favorable for the growth of acne-causing bacteria. Salicylic acid's efficacy in treating various skin conditions, particularly acne, has been extensively documented in the scientific literature. Studies have consistently shown its ability to reduce acne lesions in terms of count and severity. Additionally, salicylic acid is highly recommended for its effectiveness in treating other skin conditions, such as psoriasis and dandruff, due to its ability to soften and remove scales and flakes from the skin.

Physiological Effects

  • Keratolytic Action: Salicylic acid is known for its ability to exfoliate the skin by dissolving the intercellular 'glue' that holds skin cells together, helping to remove dead skin cells and unclog pores.
  • Comedolytic Effect: It is particularly effective in reducing comedones (blackheads and whiteheads) by unclogging pores and preventing the formation of new comedones.
  • Anti-inflammatory Properties: Salicylic acid reduces inflammation, which is beneficial in treating acne and other inflammatory skin conditions.
  • Sebum Regulation: It helps to regulate oil production, making it a valuable ingredient for managing oily and acne-prone skin.
  • Penetration Enhancement: Due to its lipophilic nature, it can penetrate sebum-filled follicles, effectively treating acne located deep within the pores.

Managing Dermatological Conditions

  • Acne Vulgaris: Salicylic acid is a cornerstone in acne treatment, effectively preventing and treating existing acne lesions.
  • Psoriasis: Its keratolytic properties make it helpful in softening and removing scales associated with psoriasis.
  • Warts: Salicylic acid is commonly used to treat warts because it can exfoliate and remove thick skin.
  • Seborrheic Dermatitis: It helps manage seborrheic dermatitis by reducing scaling and redness.
  • Keratosis Pilaris: Salicylic acid can aid in smoothing the rough bumps associated with keratosis pilaris.

References

  • Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., & Thiboutot, D. M. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973.e33.
  • Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, cosmetic and investigational dermatology, 3, 135.
  • Zander, E., & Weisman, S. (1992). Treatment of acne vulgaris with salicylic acid pads. Clinical Therapeutics.
  • Gupta, A. K., & Nicol, K. (2004). The use of sulfur in dermatology. Journal of Drugs in Dermatology.
Salicylic acid | 30%

Salicylic acid | 30%

Salicylic acid, a renowned beta hydroxy acid (BHA), is a cornerstone in dermatology and skincare due to its exceptional keratolytic and comedolytic properties. Its unique ability to penetrate oil-laden hair follicle pores makes it particularly effective in treating acne-prone and oily skin types.

Salicylic acid dissolves skin debris (sebum and dead skin cells) that clogs pores and causes acne. It's a mild antibacterial and powerful anti-inflammatory agent that helps reduce the redness and swelling associated with breakouts.

What sets salicylic acid apart in dermatological treatments is its ability to exfoliate the skin, not just on the surface but within the pores themselves. This is due to its oil-soluble nature, which allows it to penetrate deep into the pores and dissolve the keratin plugs that lead to blackheads and whiteheads.

Furthermore, salicylic acid also has the capacity to adjust the pH of the skin, creating an environment less favorable for the growth of acne-causing bacteria. Salicylic acid's efficacy in treating various skin conditions, particularly acne, has been extensively documented in the scientific literature. Studies have consistently shown its ability to reduce acne lesions in terms of count and severity. Additionally, salicylic acid is highly recommended for its effectiveness in treating other skin conditions, such as psoriasis and dandruff, due to its ability to soften and remove scales and flakes from the skin.

Physiological Effects

  • Keratolytic Action: Salicylic acid is known for its ability to exfoliate the skin by dissolving the intercellular 'glue' that holds skin cells together, helping to remove dead skin cells and unclog pores.
  • Comedolytic Effect: It is particularly effective in reducing comedones (blackheads and whiteheads) by unclogging pores and preventing the formation of new comedones.
  • Anti-inflammatory Properties: Salicylic acid reduces inflammation, which is beneficial in treating acne and other inflammatory skin conditions.
  • Sebum Regulation: It helps to regulate oil production, making it a valuable ingredient for managing oily and acne-prone skin.
  • Penetration Enhancement: Due to its lipophilic nature, it can penetrate sebum-filled follicles, effectively treating acne located deep within the pores.

Managing Dermatological Conditions

  • Acne Vulgaris: Salicylic acid is a cornerstone in acne treatment, effectively preventing and treating existing acne lesions.
  • Psoriasis: Its keratolytic properties make it helpful in softening and removing scales associated with psoriasis.
  • Warts: Salicylic acid is commonly used to treat warts because it can exfoliate and remove thick skin.
  • Seborrheic Dermatitis: It helps manage seborrheic dermatitis by reducing scaling and redness.
  • Keratosis Pilaris: Salicylic acid can aid in smoothing the rough bumps associated with keratosis pilaris.

References

  • Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., & Thiboutot, D. M. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973.e33.
  • Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, cosmetic and investigational dermatology, 3, 135.
  • Zander, E., & Weisman, S. (1992). Treatment of acne vulgaris with salicylic acid pads. Clinical Therapeutics.
  • Gupta, A. K., & Nicol, K. (2004). The use of sulfur in dermatology. Journal of Drugs in Dermatology.
Excelerate Excelerate Excelerate Excelerate
DermExcel™ | Excelerate
Excelerate Sale priceR 202.00
  • Acne: Potent Salicylic Acid content, to target moderate to severe acne lesions.
  • Congested Pores: Excelerate penetrate the pores to dissolve oil and cell debris to unclog pores.
  • Whiteheads and Blackheads: It effectively treats these comedones by promoting the shedding of cells in the follicular lining.
  • Folliculitis: A condition characterized by inflammation of hair follicles. By inhibiting the growth of bacteria that contribute to folliculitis, Excelerate alleviate symptoms and reduce the occurrence of this skin condition.
  • Bacterial Infiltration: Inhibit the growth and reduce bacterial colonization on the skin.
  • Inflammation: The treatment's anti-inflammatory properties help reduce redness, swelling, and discomfort associated with Acne, Rosacea and other conditions.
  • Seborrhea: Aid in balancing oil secretion, making it beneficial for managing seborrhea or excessively oily skin.
  • Keratosis Pilaris: Excelerate promote exfoliation and reduce skin build-up - managing this condition that cause rough, bumpy skin.
evening
  • Application time: Evening.
  • Frequency: Once or twice a month, depending on tolerability and lesion severity.
1. Cleanse
  • Start with clean and dry skin.
  • Use your DermExcel cleanser to remove dirt and excess oil from your skin.
2. Apply
  • Apply on affected areas once or twice a month, depending on tolerability and lesion severity.
  • Leave on for at least 30 minutes or overnight. If your skin burns beyond tolerability, rinse off.
  • Avoid sensitive areas like eyelids and lips.
Important Note
  • Excelerate should be used as directed and is recommended for individuals seeking a targeted solution to acne concerns.
  • As with any acne treatment, it is advisable to consult with a healthcare professional or dermatologist to determine the most suitable strength and usage guidelines for your skin type and condition.
  • Always use SPF 30 or greater during the day.

Active ingredients
  • Salicylic acid | 15%

    • Salicylic acid | 15%

  • Salicylic acid | 30%

    • Salicylic acid | 30%

Full Ingredient list

    Salicylic acid: 15% / Salicylic acid: 30%

FDA Category Indication
CFR 21, 333.310 acne
CFR 21, 358.710 (b) Seborrheic Dermatitis
CFR 21, 358.710 (c) Psoriasis

Excelerate

product benefits

Targeted Acne Treatment

Targeted Acne Treatment

Promote cellular turnover, reduce pore congestion, eliminate acne-causing bacteria, and down-regulate inflammation, resulting in a smooth and healthy complexion.

Renew skin cells

Renew skin cells

Promote cell turnover by accelerating the removal of dead skin cells and stimulating the regeneration of new cells, resulting in a smoother, more radiant complexion.

Unblock clogged pores

Unblock clogged pores

Penetrate deeply into pores to dissolve excess sebum and debris, minimizing the risk of acne formation and enlarged pores.

Anti-inflammatory

Anti-inflammatory

Alleviates skin irritation and redness by targeting inflammatory pathways and markers, offering significant relief for inflamed skin conditions.

Indications for Excelerate

Facial and Body Acne
Folliculitis
Keratosis Pilaris
Inflammation
Clogged Pores
blackheads
whiteheads
Chemical peel treatment
Target acne and Blackheads
Unclog pores
Keratosis Pilaris Treatment
High Potency

Excelerate

Mode of action

salicylic acid targets all phases of the acne process

Process
  • The first step in forming a blemish involves sebum, a naturally occurring oily substance that moisturizes, lubricates, and protects the skin and hair. While sebum production is normal, too much can lead to clogged pores.

______

Targeted treatment
  • Salicylic acid balances sebum levels because it is lipid or oil-soluble. So, rather than remaining on the skin's surface, salicylic acid penetrates deep into sebum-filled pores. 

FDA OTC Drug Monograph

Salicylic acid 3%

The US Food and Drug Administration (FDA) approves salicylic acid in OTC drug products.

In addition to being FDA-approved as a safe and effective acne drug, it is also approved for use in OTC drugs for corn, callus, wart removal, and anti-dandruff drug products.

FDA CategoryIndication
CFR 21, 333.310 acne
CFR 21, 358.710 (b) Seborrheic Dermatitis
CFR 21, 358.710 (c) Psoriasis

salicylic acid

pore clearing action

Sebum (oil) and dead skin cells accumulate inside the pores, causing blackheads and whiteheads.

Salicylic acid has the unique ability to penetrate the pores and to dissolve and extract the oil and dead skin cell plug.

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the stages of acne

Regulate sebum (oil) production and secretion

Regulate sebum (oil) production and secretion

  • The excretion of lipids by the sebaceous glands is controlled hormonally.
  • The sebaceous glands are located all over the body but are the largest and most numerous in the face, back, chest, and shoulders.
  • These glands become more active during puberty because of increased androgens, particularly testosterone, which spurs sebum production.
  • This imbalance between sebum production and secretion capacity leads to a blockage of sebum in the hair follicle, followed by inflammation.
  • Hormones continue to affect sebaceous gland activity into adulthood.
Prevent and remove content build-up in pores

Prevent and remove content build-up in pores

  • The first stage of acne is called comedogenesis (formation of comedones).
  • The exfoliated dead skin cells stick together inside the hair follicle, resulting in a clogged pore or comedone.
  • This is caused by several factors, including increased amounts of sebum, inflammation of the sides of the hair follicle preventing the release of the exfoliated keratinocytes, and increased cohesion of keratinocytes.
  • Salicylic acid decongests pores by dissolving and extracting dirt, oil, and cellular debris (dead skin cells) in the pores and follicles.
Prevent Bacterial Infiltration and infection

Prevent Bacterial Infiltration and infection

  • The keratinocyte plug and sebum provide excellent food sources for bacteria.
  • The bacteria invade the comedone and release inflammatory factors that lead to the next stage of acne.
  • Salicylic acid inhibits the production of various aspects necessary for bacterial reproduction, such as fibrinogen, fibronectin, and alpha-hemolysis.
Down-regulate and prevent inflammation

Down-regulate and prevent inflammation

  • Inflammation continues with increased redness and pus.
  • This is clinically detectable as a papule or pustule.
  • Continued inflammation may lead to so much inflammation that the hair follicle ruptures and the bacteria and debris are released into the dermis.
  • Salicylic acid suppresses pro-inflammatory cytokine expression.

mode of action

salicylic acid as acne treatment

Keratolytic

Keratolytic

Disrupts cellular junctions to exfoliate dead skin, revealing bright, new cells.

Comedolytic

Comedolytic

Unclog pores by dissolving and extracting dirt, oil, and cellular debris.

Anti-bacterial

Anti-bacterial

Inhibits bacteria responsible for causing and aggravating acne and rosacea.

anti-inflammatory

anti-inflammatory

Inhibit the inflammation that leads to breakouts, redness, and skin damage.

Testimonials

Customer Reviews

Based on 467 reviews
94%
(440)
4%
(20)
1%
(6)
0%
(0)
0%
(1)
T
Talita
Great product!

I can definitely see improvement in breakouts. Looking forward in seeing results in the next month or 2.

S
Shanté Marais
Overnight Miracle

I've been using the glycolic gel for almost a year now, and I am absolutely thrilled with the results! It's like an overnight miracle for my skin—every time I apply it, I wake up to smoother, more radiant skin. At first, it took a little time for my face to adjust, but once it did, there was no turning back. I highly recommend it. 5/5 from me!

J
Janke van der Linde
Glycolig Gel

Love love love!!! Saw a difference after 2 weeks!

C
Carin le Roux
Love this product.

Makes my skin super smooth and soft.

L
Leandra Saayman
Excellent

There is no product better than Dermalhealth.

C
Cheryl de Villiers
Awesome Glycolic Gel

Dermexcel’s Glycolic Gel is my goto night treatment. I love how my skin looks and feels when I wake up.

123
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