Excelerate

DermExcel™

Excelerate

R 202.00

4.9 / 5.0 from 470 reviews

Pay interest-free installments from R 50.50 with various payment gateways selected at checkout.

Size:

Strength:

Variant

↓ Sebum

Unclog Pores

Ingrown hair

Anti-Acne

↓ inflammation

A high-potency Salicylic acid treatment available in two strengths – 15% and 30%. This efficacious formulation is designed to systematically counteract acne formation by addressing the critical stages of acne development: comedones, bacteria, and inflammation. It maintains a balance in oil secretion, and its unique keratolytic action accelerates the turnover of skin cells, fostering flaking on the epidermis and inside the pores. This process aids in unclogging pores, a fundamental step in acne management.

The powerful antibacterial properties of Salicylic acid in Excelerate combat acne-causing bacteria, inhibiting their growth and reducing their presence on the skin. This targeted action helps to clear existing acne lesions and prevent the formation of new ones, promoting a clearer complexion. It also down-regulates the inflammatory response associated with acne. Reducing redness and swelling helps soothe the visible signs of inflammation, relieving troubled skin.

Excelerate's dual strengths offer flexibility in treatment options, allowing individuals to choose the appropriate concentration based on their specific needs and skin sensitivity. The 15% strength provides a gentle yet effective approach, while the 30% strength offers a more intensive treatment for stubborn or severe acne.

Excelerate should be used as directed and is recommended for individuals seeking a targeted solution to acne concerns. As with any acne treatment, it is advisable to consult with a healthcare professional or dermatologist to determine the most suitable strength and usage guidelines for your individual skin type and condition.

SHIPPING

Shipping Guarantee: Guiding you to healthy skin isn’t only about our products; it's also about getting them to you as swiftly as the science behind them. That's why Dermal Health offers a shipping guarantee you can rely on.
Where We Ship From: Orders are dispatched from our facilities in Pretoria.
Who We Ship With: We trust only well-known, popular, and dependable courier services with your packages.
When You'll Get It: Expect confident skin soon! Shipping addresses in Pretoria and Johannesburg will enjoy delivery from same-day to 2 business days. Shipping addresses further from Pretoria may expect delivery within 1-4 business days, depending on the service you select during checkout. Your estimated delivery date will reflect during checkout so that you can mark your calendar.
Tracking Your Order: Eager to start your DermExcel journey? We don't blame you! You'll receive a tracking number after you place your order so that you can follow your package.

For any shipping inquiries, our customer service team is ready to assist.

RETURNS

We are passionate about guiding you to healthier skin through medical science. We believe in the quality and proven effectiveness of our formulations — and we’re committed to supporting you on your journey to real, visible results.

That’s why we offer a 30-Day Confidence Guarantee. If, after consistent use as directed, you genuinely feel that your skin has not improved in any meaningful way — and you can demonstrate this (for example, with before-and-after photos or a brief description of your experience) — you’re welcome to request a return within 30 days of receiving your order, in line with our return policy.

Healthy skin is not complicated — and neither is our return process. To view the full terms, please visit our detailed return policy or contact our friendly customer care team. We’re here to help.

Feel as confident in us as we want you to feel in your skin.

SECURE PAYMENT

Dermal Health Science 30-Day Confidence Guarantee: We are passionate about guiding you to healthy skin through medical science. We believe in the quality and effectiveness of our products so much that we offer a 30-Day Confidence Guarantee.

If you're unsatisfied with your purchase, simply return it within 30 days for a full refund.

Healthy Skin Is Not Complicated and neither is our return policy. Please visit our detailed return policy or contact our friendly customer service team for more information.

Feel as confident in us as we want you to feel in your skin.

Excelerate

R 202.00

Acne: Potent Salicylic Acid content, to target moderate to severe acne lesions.
Congested Pores: Excelerate penetrate the pores to dissolve oil and cell debris to unclog pores.
Whiteheads and Blackheads: It effectively treats these comedones by promoting the shedding of cells in the follicular lining.
Folliculitis: A condition characterized by inflammation of hair follicles. By inhibiting the growth of bacteria that contribute to folliculitis, Excelerate alleviate symptoms and reduce the occurrence of this skin condition.
Bacterial Infiltration: Inhibit the growth and reduce bacterial colonization on the skin.
Inflammation: The treatment's anti-inflammatory properties help reduce redness, swelling, and discomfort associated with Acne, Rosacea and other conditions.
Seborrhea: Aid in balancing oil secretion, making it beneficial for managing seborrhea or excessively oily skin.
Keratosis Pilaris: Excelerate promote exfoliation and reduce skin build-up - managing this condition that cause rough, bumpy skin.

Evening

Application time: Evening.
Frequency: Once or twice a month, depending on tolerability and lesion severity.

1. Cleanse

Start with clean and dry skin.
Use your DermExcel cleanser to remove dirt and excess oil from your skin.

2. Apply

Apply on affected areas once or twice a month, depending on tolerability and lesion severity.
Leave on for at least 30 minutes or overnight. If your skin burns beyond tolerability, rinse off.
Avoid sensitive areas like eyelids and lips.

Important note

Excelerate should be used as directed and is recommended for individuals seeking a targeted solution to acne concerns.
As with any acne treatment, it is advisable to consult with a healthcare professional or dermatologist to determine the most suitable strength and usage guidelines for your skin type and condition.
Always use SPF 30 or greater during the day.

Active ingredients

Salicylic acid | 15%

Salicylic acid | 30%

Full Ingredient list

Salicylic acid: 15% / Salicylic acid: 30%

Excelerate

product benefits

Targeted Acne Treatment

Promote cellular turnover, reduce pore congestion, eliminate acne-causing bacteria, and down-regulate inflammation, resulting in a smooth and healthy complexion.

Renew skin cells

Promote cell turnover by accelerating the removal of dead skin cells and stimulating the regeneration of new cells, resulting in a smoother, more radiant complexion.

Unblock clogged pores

Penetrate deeply into pores to dissolve excess sebum and debris, minimizing the risk of acne formation and enlarged pores.

Anti-inflammatory

Alleviates skin irritation and redness by targeting inflammatory pathways and markers, offering significant relief for inflamed skin conditions.

Indications for Excelerate

Facial and Body Acne
Folliculitis
Keratosis Pilaris
Inflammation
Clogged Pores
blackheads
whiteheads

Chemical peel treatment

Target acne and Blackheads

Unclog pores

Keratosis Pilaris Treatment

High Potency

Excelerate

Mode of action

Exfoliating

Salicylic acid works well to balance sebum levels because it is lipid or oil-soluble. So, rather than remaining on the skin's surface, Salicylic acid penetrates deep into sebum-filled pores.
Salicylic acid works by loosening and breaking apart desmosomes (attachments between cells in the outer layers of the skin). This action encourages the exfoliation of dead and damaged skin and unclogging pores.
Disrupts cellular junctions to exfoliate dead skin cells.

Unclog Pores

Salicylic acid is lipophilic, which means it can penetrate oily skin and clogged pores, resulting in deep cleaning.
Decongests pores by dissolving and extracting dirt, oil, and cellular debris in the pores and follicles.

Regulate Sebum (oil)

Salicylic acid works well to balance sebum levels because it is lipid or oil-soluble. So, rather than remaining on the skin's surface, Salicylic acid penetrates deep into sebum-filled pores.

Microbial Control

It inhibits the production of various aspects necessary for bacterial reproduction, such as fibrinogen, fibronectin, and alpha-hemolysis. Therefore, salicylic acid may neutralize the bacteria C. acnes in blemishes.

anti-inflammatory & anti-acne

Salicylic acid reduces sebum secretion.
Salicylic acid has potent anti-inflammatory effects, inhibiting the arachidonic acid cascade.
Salicylic acid reduces inflammation by modulating COX2 gene expression to decrease the formation of pro-inflammatory cytokines.

salicylic acid targets all phases of the acne process

Process

The first step in forming a blemish involves sebum, a naturally occurring oily substance that moisturizes, lubricates, and protects the skin and hair. While sebum production is normal, too much can lead to clogged pores.

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Targeted treatment

Salicylic acid balances sebum levels because it is lipid or oil-soluble. So, rather than remaining on the skin's surface, salicylic acid penetrates deep into sebum-filled pores.

Sebum over-production

Process

The first step in forming a blemish involves sebum, a naturally occurring oily substance that moisturizes, lubricates, and protects the skin and hair. While sebum production is normal, too much can lead to clogged pores.

______

Targeted treatment

Salicylic acid balances sebum levels because it is lipid or oil-soluble. So, rather than remaining on the skin's surface, salicylic acid penetrates deep into sebum-filled pores.

Clogged pores

Process

The next step in the development of acne is triggered when the skin's follicles are not exfoliating properly. This means keratin, a protein found within the skin, and sebum clog the follicle.

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Targeted treatment

Salicylic acid decongests pores by dissolving and extracting dirt, oil, and cellular debris in the pores and follicles.
Salicylic acid disrupts cellular junctions to exfoliate dead skin cells.

Bacterial infiltration

Process

When the follicle becomes clogged, a species of bacteria called Cutibacterium acnes (formerly Propionibacterium acnes) accumulates and multiplies in the follicle.

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Targeted treatment

Salicylic acid inhibits the production of various aspects necessary for bacterial reproduction, such as fibrinogen, fibronectin, and alpha-hemolysis.

Inflammation

Process

After bacterial infiltration the follicle becomes inflamed, thus leading to pimple formation.

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Targeted treatment

Salicylic acid suppresses pro-inflammatory cytokine expression.
Salicylic acid inhibits the arachidonic acid cascade.

FDA OTC Drug Monograph

Salicylic acid 3%

The US Food and Drug Administration (FDA) approves salicylic acid in OTC drug products.

In addition to being FDA-approved as a safe and effective acne drug, it is also approved for use in OTC drugs for corn, callus, wart removal, and anti-dandruff drug products.

FDA Category	Indication
CFR 21, 333.310	acne
CFR 21, 358.710 (b)	seborrheic dermatitis
CFR 21, 358.710 (c)	psoriasis

salicylic acid

pore clearing action

Sebum (oil) and dead skin cells accumulate inside the pores, causing blackheads and whiteheads.

Salicylic acid has the unique ability to penetrate the pores and to dissolve and extract the oil and dead skin cell plug.

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the stages of acne

Regulate sebum (oil) production and secretion

The excretion of lipids by the sebaceous glands is controlled hormonally.
The sebaceous glands are located all over the body but are the largest and most numerous in the face, back, chest, and shoulders.
These glands become more active during puberty because of increased androgens, particularly testosterone, which spurs sebum production.
This imbalance between sebum production and secretion capacity leads to a blockage of sebum in the hair follicle, followed by inflammation.
Hormones continue to affect sebaceous gland activity into adulthood.

Prevent and remove content build-up in pores

The first stage of acne is called comedogenesis (formation of comedones).
The exfoliated dead skin cells stick together inside the hair follicle, resulting in a clogged pore or comedone.
This is caused by several factors, including increased amounts of sebum, inflammation of the sides of the hair follicle preventing the release of the exfoliated keratinocytes, and increased cohesion of keratinocytes.
Salicylic acid decongests pores by dissolving and extracting dirt, oil, and cellular debris (dead skin cells) in the pores and follicles.

Prevent Bacterial Infiltration and infection

The keratinocyte plug and sebum provide excellent food sources for bacteria.
The bacteria invade the comedone and release inflammatory factors that lead to the next stage of acne.
Salicylic acid inhibits the production of various aspects necessary for bacterial reproduction, such as fibrinogen, fibronectin, and alpha-hemolysis.

Down-regulate and prevent inflammation

Inflammation continues with increased redness and pus.
This is clinically detectable as a papule or pustule.
Continued inflammation may lead to so much inflammation that the hair follicle ruptures and the bacteria and debris are released into the dermis.
Salicylic acid suppresses pro-inflammatory cytokine expression.

mode of action

salicylic acid as acne treatment

Keratolytic

Disrupts cellular junctions to exfoliate dead skin, revealing bright, new cells.

Comedolytic

Unclog pores by dissolving and extracting dirt, oil, and cellular debris.

Anti-bacterial

Inhibits bacteria responsible for causing and aggravating acne and rosacea.

anti-inflammatory

Inhibit the inflammation that leads to breakouts, redness, and skin damage.

Testimonials

Glycolic Gel

Seems good!

I have used the product once as it requires you to wait 4 weeks between doses, I’ve seen results after one cycle and look forward to applying it now a second time and for the results! 🤩

Dermalytic

It works wonders on hyperpigmentation, fades away the dark marks.

Great product!

I can definitely see improvement in breakouts. Looking forward in seeing results in the next month or 2.

Overnight Miracle

I've been using the glycolic gel for almost a year now, and I am absolutely thrilled with the results! It's like an overnight miracle for my skin—every time I apply it, I wake up to smoother, more radiant skin. At first, it took a little time for my face to adjust, but once it did, there was no turning back. I highly recommend it. 5/5 from me!