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DermExcel™ | Dermdefence SPF 50
DermExcel™ | Dermdefence SPF 50
DermExcel™ | Dermdefence SPF 50
DermExcel™ | Dermdefence SPF 50
DermExcel™ | Dermdefence SPF 50
Dermdefence SPF 50: Trial Dermdefence SPF 50: Trial Dermdefence SPF 50: Trial Dermdefence SPF 50: Trial
DermExcel™

Dermdefence SPF 50: Trial

4.9 / 5.0 from 805 reviews
Sale priceR 61.00

SIZE: 5 mL

Antioxidant

Antioxidant

anti-aging

anti-aging

DNA repair

DNA repair

sun protection

sun protection

Moisturizing

Moisturizing

A pioneering sunscreen offering superior protection against the sun while preserving your skin's cellular and DNA health. The innovative formula exceeds standard UV protection, guarding against UVA, UVB, damaging infrared rays, and blue light. Offering wide-ranging protection bolsters your skin's restorative abilities, promoting a healthier and more resilient complexion.

Designed to be fragrance-free and anti-comedogenic, Dermdefence SPF 50 ensures no skin irritation or pore clogging, making it an excellent choice for those with skin conditions like Acne, Rosacea, or Eczema. Its lightweight, non-greasy texture provides easy application and rapid absorption, without leaving a white cast.

Dermdefence SPF 50 also serves as a primer, providing a smooth finish for easy makeup application and ensuring a flawless look all day. Dermdefence SPF 50 provides unparalleled sun protection that will shield your skin and nurture its unique needs, maintaining its health and radiance.

Coenzyme Q10
Coenzyme Q10

CoQ10 is a potent ingredient that offers comprehensive skin health and appearance benefits. Its role in energy production and its antioxidant and anti-aging properties make it invaluable for photoprotection, anti-aging, and overall skin vitality. Its incorporation into DermExcel sunscreen represents a holistic approach to skin health, addressing protective and restorative needs.

Physiological Impact
  • Skin Barrier Enhancement: CoQ10 contributes to the strength and health of the skin barrier, improving its ability to retain moisture and protect against external irritants and pollutants.
  • Skin Repair and Regeneration: It supports the skin's natural ability to repair itself and regenerate, maintaining a healthy, youthful appearance. This is particularly beneficial in mature skin, where natural levels of CoQ10 may be depleted.

Pharmacological Advantages
  • Anti-Aging Effects: CoQ10's antioxidant properties contribute to its anti-aging effects. By reducing oxidative stress, it helps to minimize the visible signs of aging, such as wrinkles and fine lines.
  • Photoprotection: It enhances the skin's defense against photoaging caused by exposure to UV rays. CoQ10 helps to mitigate the degradation of collagen and elastin, proteins essential for maintaining skin elasticity and firmness.

Biochemical Benefits
  • Cellular Energy Production: CoQ10 plays a crucial role in the mitochondrial electron transport chain, which is essential for the production of ATP, the primary energy currency of the cell. This function is vital for maintaining the health and vitality of skin cells.
  • Antioxidant Properties: It acts as a lipophilic antioxidant, neutralizing free radicals and preventing oxidative damage to cell membranes, proteins, and DNA. This is particularly important in the skin, which is frequently exposed to oxidative stress from environmental factors like UV radiation.
Infraguard™
Infraguard™

Infraguard™ is a novel and powerful antioxidant powerhouse designed to protect the skin from the potentially harmful effects of electromagnetic radiation, specifically from 5G networks, blue light, and other environmental stressors. It shields the skin against oxidative stress and inflammation, prevents premature aging, and maintains overall health.

Infraguard® is a multifunctional ingredient that extends beyond traditional sun protection. It addresses the broader spectrum of light-induced skin damage and oxidative stress, provides DNA protection, and offers anti-aging benefits. Its inclusion in the DermExcel sunscreens represents an advanced step in comprehensive skin care, targeting UV rays and the often-overlooked infrared and blue light, ensuring a more holistic approach to maintaining skin health and appearance.

Physiological Effects
  • Protection Against Blue Light and Infrared (IR) Radiation: Infraguard is formulated to shield the skin from the harmful effects of blue light and IR radiation, which can lead to premature skin aging and damage.
  • Antioxidant Properties: It has strong antioxidant capabilities, helping to neutralize free radicals induced by environmental stressors such as pollution, IR, and blue light.
  • Anti-Aging Benefits: By protecting against IR radiation and mitigating oxidative stress, Infraguard helps to prevent signs of aging like wrinkles and loss of skin elasticity.
  • Skin Barrier Protection: Infraguard strengthens the skin's natural barrier, enhancing its resilience against environmental factors.
  • DNA Protection: Infraguard™ aids in shielding the DNA in skin cells from damage caused by environmental aggressors. This is crucial in maintaining the integrity of skin cells and preventing mutations that can lead to skin aging and other skin-related issues.

Role in Managing Dermatological Conditions
  • Preventing Photoaging: Infraguard's ability to protect against IR and blue light makes it beneficial in preventing photoaging, a key concern in modern dermatology. Infrared light can penetrate deeper into the skin than UV rays, potentially leading to increased collagen degradation and skin laxity. Infraguard® helps mitigate these effects.
  • Combatting Environmental Stressors: Its antioxidant properties protect the skin from various environmental pollutants and stressors.
  • Supporting Skin Health: Infraguard contributes to overall skin health by improving the skin's barrier function and providing antioxidant support.
  • Suitability for Diverse Skin Conditions: Given its protective and anti-aging properties, Infraguard is suitable for use in various dermatological conditions, especially environmental damage and aging.

References
  • Kappler, Katharina et al. "Development of an in Vitro Assay to Evaluate the Biological Impact of 5G Technology on Human Skin. Journal of Cosmetics, Dermatological Sciences and Applications, 2022, vol. 12, pp. 100-108. DOI: 10.4236/jcdsa.2022.122009​​.
  • Extensive references cited within the research article including studies on 5G technology, health effects, and skin biology​​.
Broad Spectrum Filters
Broad Spectrum Filters

Tinosorb® M and Tinosorb® S represent sophisticated advancements in sun protection technology.

Tinosorb® M
  • Biochemical Action: A unique UV filter due to its ability to function through absorption, reflection, and scattering of UV rays.
  • Physiological Impact: The triple-action mechanism of Tinosorb® M offers comprehensive sun protection. By mitigating the penetration of both UVA and UVB rays, it significantly reduces the risk of DNA damage, photoaging, and carcinogenesis. Its ability to remain on the skin's surface reduces systemic exposure, making it a safer option with minimal potential for irritation or allergic reactions.

Tinosorb® S
  • Biochemical Action: A broad-spectrum UV filter with a molecular structure that effectively absorbs both UVA and UVB rays. Additionally, it enhances the photostability of other UV filters, making the sunscreen formulation more effective over time.
  • Physiological Impact: By providing extensive UVA and UVB protection, Tinosorb® S plays a crucial role in preventing short-term sun damage like sunburn and long-term risks such as skin aging and skin cancer. Its photostability ensures sustained protection during sun exposure, and its compatibility with other UV filters means it can be used to formulate sunscreens that are both effective and suitable for sensitive skin.
Sunscreen
Sunscreen

Using sunscreen is a fundamental aspect of skin care and preventive dermatology. It's essential for reducing the risk of skin cancers and photoaging and maintaining overall skin health in the face of constant exposure to UV radiation.

Sunscreen is a vital skincare product designed to protect the skin from the harmful effects of ultraviolet (UV) radiation from the sun. Two primary types of UV radiation affect the skin: UVA and UVB. UVA rays penetrate deep into the skin and are primarily responsible for aging and long-term skin damage, whereas UVB rays cause sunburn and play a key role in developing skin cancer.

Sunscreen products work by either absorbing, reflecting, or scattering sunlight. They contain chemical compounds that absorb UV radiation and convert it into a small amount of heat or physical compounds (like zinc oxide or titanium dioxide) that act as a physical barrier, reflecting UV light away from the skin.

The effectiveness of sunscreen is measured by its Sun Protection Factor (SPF). SPF indicates how well the sunscreen protects against UVB rays. For example, an SPF of 30 means it would take 30 times longer for your skin to burn than without sunscreen. However, it's important to note that no sunscreen can block 100% UV rays.

Regular use of sunscreen with an SPF of at least 30 can reduce the risk of skin cancer, prevent sunburn, and slow down the skin's aging process.

Role in Managing Dermatological Conditions
Prevention of Sunburn
  • UVB Protection: Sunscreen protects the skin from UVB rays, which cause sunburn. This reduces the immediate risk of skin damage and discomfort.
Skin Cancer Prevention
  • Reduces Risk of Skin Cancers: Regular use of sunscreen significantly lowers the risk of developing various types of skin cancer, especially melanoma, squamous cell carcinoma, and basal cell carcinoma.
Prevention of Photoaging
  • UVA Protection: Sunscreen also shields the skin from UVA rays, which penetrate deeper into the skin and are primarily responsible for photoaging, including wrinkles, leathery skin, and sunspots.
Protection Against Photosensitivity
  • Essential for Sensitive Skin Conditions: Sunscreen helps prevent flare-ups triggered by sun exposure for individuals with photosensitive skin conditions like lupus or rosacea.
Hyperpigmentation and Melasma
  • Even Skin Tone: It aids in preventing and managing hyperpigmentation and melasma, conditions exacerbated by sun exposure.
General Skin Health
  • Maintains Skin Health: Sunscreen helps maintain overall skin health and integrity by protecting the skin from UV damage.

References
  • Burnett, M. E., & Wang, S. Q. (2011). Current sunscreen controversies: a critical review. Photodermatology, Photoimmunology & Photomedicine.
  • Green, A. C., et al. (2011). Reduced melanoma after regular sunscreen use: randomized trial follow-up. Journal of Clinical Oncology.
  • Hughes, M. C. B., et al. (2013). Sunscreen and Prevention of Skin Aging: A Randomized Trial. Annals of Internal Medicine.
Dermdefence SPF 50: Trial Dermdefence SPF 50: Trial Dermdefence SPF 50: Trial Dermdefence SPF 50: Trial
DermExcel™ | Dermdefence SPF 50
Dermdefence SPF 50: Trial Sale priceR 61.00
  • Sun Protection: Provide broad-spectrum protection against UVA, UVB, infrared rays, and blue light, safeguarding your skin's cellular and DNA health.
  • Anti-Aging: Prevent UV radiation-induced redness, and free radical formation - protecting against the main source of skin aging.
  • Sensitive Skin Conditions: Suitable for skin conditions like Acne, Rosacea, or Eczema as it's non-irritating and won't clog pores.
  • Daily Moisturizing: Suitable for daily use to keep skin moisturized and protected.
  • Primer Before Makeup: Effective primer, providing a smooth base for makeup application.
  • Skin Comfort: Lightweight formula that absorbs quickly without leaving any white residue.

Active ingredients
  • Coenzyme Q10
    • Coenzyme Q10

    Using sunscreen is a fundamental aspect of skin care and preventive dermatology. It's essential for reducing the risk of skin cancers and photoaging and maintaining overall skin health in the face of constant exposure to UV radiation.

    Sunscreen is a vital skincare product designed to protect the skin from the harmful effects of ultraviolet (UV) radiation from the sun. Two primary types of UV radiation affect the skin: UVA and UVB. UVA rays penetrate deep into the skin and are primarily responsible for aging and long-term skin damage, whereas UVB rays cause sunburn and play a key role in developing skin cancer.

    Sunscreen products work by either absorbing, reflecting, or scattering sunlight. They contain chemical compounds that absorb UV radiation and convert it into a small amount of heat or physical compounds (like zinc oxide or titanium dioxide) that act as a physical barrier, reflecting UV light away from the skin.

    The effectiveness of sunscreen is measured by its Sun Protection Factor (SPF). SPF indicates how well the sunscreen protects against UVB rays. For example, an SPF of 30 means it would take 30 times longer for your skin to burn than without sunscreen. However, it's important to note that no sunscreen can block 100% UV rays.

    Regular use of sunscreen with an SPF of at least 30 can reduce the risk of skin cancer, prevent sunburn, and slow down the skin's aging process.
    Prevention of Sunburn
    • UVB Protection: Sunscreen protects the skin from UVB rays, which cause sunburn. This reduces the immediate risk of skin damage and discomfort.
    Skin Cancer Prevention
    • Reduces Risk of Skin Cancers: Regular use of sunscreen significantly lowers the risk of developing various types of skin cancer, especially melanoma, squamous cell carcinoma, and basal cell carcinoma.
    Prevention of Photoaging
    • UVA Protection: Sunscreen also shields the skin from UVA rays, which penetrate deeper into the skin and are primarily responsible for photoaging, including wrinkles, leathery skin, and sunspots.
    Protection Against Photosensitivity
    • Essential for Sensitive Skin Conditions: Sunscreen helps prevent flare-ups triggered by sun exposure for individuals with photosensitive skin conditions like lupus or rosacea.
    Hyperpigmentation and Melasma
    • Even Skin Tone: It aids in preventing and managing hyperpigmentation and melasma, conditions exacerbated by sun exposure.
    General Skin Health
    • Maintains Skin Health: Sunscreen helps maintain overall skin health and integrity by protecting the skin from UV damage.
    • Burnett, M. E., & Wang, S. Q. (2011). Current sunscreen controversies: a critical review. Photodermatology, Photoimmunology & Photomedicine.
    • Green, A. C., et al. (2011). Reduced melanoma after regular sunscreen use: randomized trial follow-up. Journal of Clinical Oncology.
    • Hughes, M. C. B., et al. (2013). Sunscreen and Prevention of Skin Aging: A Randomized Trial. Annals of Internal Medicine.
  • Infraguard™
    • Infraguard™

    Using sunscreen is a fundamental aspect of skin care and preventive dermatology. It's essential for reducing the risk of skin cancers and photoaging and maintaining overall skin health in the face of constant exposure to UV radiation.

    Sunscreen is a vital skincare product designed to protect the skin from the harmful effects of ultraviolet (UV) radiation from the sun. Two primary types of UV radiation affect the skin: UVA and UVB. UVA rays penetrate deep into the skin and are primarily responsible for aging and long-term skin damage, whereas UVB rays cause sunburn and play a key role in developing skin cancer.

    Sunscreen products work by either absorbing, reflecting, or scattering sunlight. They contain chemical compounds that absorb UV radiation and convert it into a small amount of heat or physical compounds (like zinc oxide or titanium dioxide) that act as a physical barrier, reflecting UV light away from the skin.

    The effectiveness of sunscreen is measured by its Sun Protection Factor (SPF). SPF indicates how well the sunscreen protects against UVB rays. For example, an SPF of 30 means it would take 30 times longer for your skin to burn than without sunscreen. However, it's important to note that no sunscreen can block 100% UV rays.

    Regular use of sunscreen with an SPF of at least 30 can reduce the risk of skin cancer, prevent sunburn, and slow down the skin's aging process.
    Prevention of Sunburn
    • UVB Protection: Sunscreen protects the skin from UVB rays, which cause sunburn. This reduces the immediate risk of skin damage and discomfort.
    Skin Cancer Prevention
    • Reduces Risk of Skin Cancers: Regular use of sunscreen significantly lowers the risk of developing various types of skin cancer, especially melanoma, squamous cell carcinoma, and basal cell carcinoma.
    Prevention of Photoaging
    • UVA Protection: Sunscreen also shields the skin from UVA rays, which penetrate deeper into the skin and are primarily responsible for photoaging, including wrinkles, leathery skin, and sunspots.
    Protection Against Photosensitivity
    • Essential for Sensitive Skin Conditions: Sunscreen helps prevent flare-ups triggered by sun exposure for individuals with photosensitive skin conditions like lupus or rosacea.
    Hyperpigmentation and Melasma
    • Even Skin Tone: It aids in preventing and managing hyperpigmentation and melasma, conditions exacerbated by sun exposure.
    General Skin Health
    • Maintains Skin Health: Sunscreen helps maintain overall skin health and integrity by protecting the skin from UV damage.
    • Burnett, M. E., & Wang, S. Q. (2011). Current sunscreen controversies: a critical review. Photodermatology, Photoimmunology & Photomedicine.
    • Green, A. C., et al. (2011). Reduced melanoma after regular sunscreen use: randomized trial follow-up. Journal of Clinical Oncology.
    • Hughes, M. C. B., et al. (2013). Sunscreen and Prevention of Skin Aging: A Randomized Trial. Annals of Internal Medicine.
  • Broad Spectrum Filters
    • Broad Spectrum Filters

    Using sunscreen is a fundamental aspect of skin care and preventive dermatology. It's essential for reducing the risk of skin cancers and photoaging and maintaining overall skin health in the face of constant exposure to UV radiation.

    Sunscreen is a vital skincare product designed to protect the skin from the harmful effects of ultraviolet (UV) radiation from the sun. Two primary types of UV radiation affect the skin: UVA and UVB. UVA rays penetrate deep into the skin and are primarily responsible for aging and long-term skin damage, whereas UVB rays cause sunburn and play a key role in developing skin cancer.

    Sunscreen products work by either absorbing, reflecting, or scattering sunlight. They contain chemical compounds that absorb UV radiation and convert it into a small amount of heat or physical compounds (like zinc oxide or titanium dioxide) that act as a physical barrier, reflecting UV light away from the skin.

    The effectiveness of sunscreen is measured by its Sun Protection Factor (SPF). SPF indicates how well the sunscreen protects against UVB rays. For example, an SPF of 30 means it would take 30 times longer for your skin to burn than without sunscreen. However, it's important to note that no sunscreen can block 100% UV rays.

    Regular use of sunscreen with an SPF of at least 30 can reduce the risk of skin cancer, prevent sunburn, and slow down the skin's aging process.
    Prevention of Sunburn
    • UVB Protection: Sunscreen protects the skin from UVB rays, which cause sunburn. This reduces the immediate risk of skin damage and discomfort.
    Skin Cancer Prevention
    • Reduces Risk of Skin Cancers: Regular use of sunscreen significantly lowers the risk of developing various types of skin cancer, especially melanoma, squamous cell carcinoma, and basal cell carcinoma.
    Prevention of Photoaging
    • UVA Protection: Sunscreen also shields the skin from UVA rays, which penetrate deeper into the skin and are primarily responsible for photoaging, including wrinkles, leathery skin, and sunspots.
    Protection Against Photosensitivity
    • Essential for Sensitive Skin Conditions: Sunscreen helps prevent flare-ups triggered by sun exposure for individuals with photosensitive skin conditions like lupus or rosacea.
    Hyperpigmentation and Melasma
    • Even Skin Tone: It aids in preventing and managing hyperpigmentation and melasma, conditions exacerbated by sun exposure.
    General Skin Health
    • Maintains Skin Health: Sunscreen helps maintain overall skin health and integrity by protecting the skin from UV damage.
    • Burnett, M. E., & Wang, S. Q. (2011). Current sunscreen controversies: a critical review. Photodermatology, Photoimmunology & Photomedicine.
    • Green, A. C., et al. (2011). Reduced melanoma after regular sunscreen use: randomized trial follow-up. Journal of Clinical Oncology.
    • Hughes, M. C. B., et al. (2013). Sunscreen and Prevention of Skin Aging: A Randomized Trial. Annals of Internal Medicine.
  • Sunscreen
    • Sunscreen

    Using sunscreen is a fundamental aspect of skin care and preventive dermatology. It's essential for reducing the risk of skin cancers and photoaging and maintaining overall skin health in the face of constant exposure to UV radiation.

    Sunscreen is a vital skincare product designed to protect the skin from the harmful effects of ultraviolet (UV) radiation from the sun. Two primary types of UV radiation affect the skin: UVA and UVB. UVA rays penetrate deep into the skin and are primarily responsible for aging and long-term skin damage, whereas UVB rays cause sunburn and play a key role in developing skin cancer.

    Sunscreen products work by either absorbing, reflecting, or scattering sunlight. They contain chemical compounds that absorb UV radiation and convert it into a small amount of heat or physical compounds (like zinc oxide or titanium dioxide) that act as a physical barrier, reflecting UV light away from the skin.

    The effectiveness of sunscreen is measured by its Sun Protection Factor (SPF). SPF indicates how well the sunscreen protects against UVB rays. For example, an SPF of 30 means it would take 30 times longer for your skin to burn than without sunscreen. However, it's important to note that no sunscreen can block 100% UV rays.

    Regular use of sunscreen with an SPF of at least 30 can reduce the risk of skin cancer, prevent sunburn, and slow down the skin's aging process.
    Prevention of Sunburn
    • UVB Protection: Sunscreen protects the skin from UVB rays, which cause sunburn. This reduces the immediate risk of skin damage and discomfort.
    Skin Cancer Prevention
    • Reduces Risk of Skin Cancers: Regular use of sunscreen significantly lowers the risk of developing various types of skin cancer, especially melanoma, squamous cell carcinoma, and basal cell carcinoma.
    Prevention of Photoaging
    • UVA Protection: Sunscreen also shields the skin from UVA rays, which penetrate deeper into the skin and are primarily responsible for photoaging, including wrinkles, leathery skin, and sunspots.
    Protection Against Photosensitivity
    • Essential for Sensitive Skin Conditions: Sunscreen helps prevent flare-ups triggered by sun exposure for individuals with photosensitive skin conditions like lupus or rosacea.
    Hyperpigmentation and Melasma
    • Even Skin Tone: It aids in preventing and managing hyperpigmentation and melasma, conditions exacerbated by sun exposure.
    General Skin Health
    • Maintains Skin Health: Sunscreen helps maintain overall skin health and integrity by protecting the skin from UV damage.
    • Burnett, M. E., & Wang, S. Q. (2011). Current sunscreen controversies: a critical review. Photodermatology, Photoimmunology & Photomedicine.
    • Green, A. C., et al. (2011). Reduced melanoma after regular sunscreen use: randomized trial follow-up. Journal of Clinical Oncology.
    • Hughes, M. C. B., et al. (2013). Sunscreen and Prevention of Skin Aging: A Randomized Trial. Annals of Internal Medicine.

Full ingredient list

    Aqua, Octyl methoxycinnamate (Uvinul® MC 80), Butyl methoxydibenzoylmethane (Avobenzone), Propylene glycol, Ethylhexyl salicylate (Octisalate), Cetyl alcohol, Glycerine, Sorbitan mono stearate, Polysorbate 20, Bis-ethylhexyloxyphenol, Methoxyphenyl triazine (Tinosorb S), Homosalate, Squalane, Ubiquinone, Phenoxyethanol, Ethylhexyl glycerine, Tocopherol (Vitamin E), Triethanolamine, Dimethicone, Acrylate crosspolymer, Disodium EDTA

Morning
  • Application time: Apply in the morning on cleansed skin.
  • Frequency: Every day.

1. Cleanse
  • Start with clean and dry skin.
  • Use your DermExcel cleanser to remove dirt and excess oil from your skin.

2. Apply
  • Apply it evenly across all sun-exposed areas every morning to safeguard your skin against the harmful effects of sun exposure.
  • During prolonged sun exposure, it's crucial to reapply as needed to maintain its protective barrier.
  • Avoid applying sunscreen on damaged or broken skin, which may cause discomfort or adverse reactions in compromised areas.
  • Be mindful when applying around the eye area. If used too close, it may cause watering or stinging. If this occurs, rinse thoroughly with water; if the problem persists, consult your healthcare provider.

indications for Dermdefence SPF 50: Trial

DNA Protection
Infrared & Blue light protection
UVA and UVB protection
Aging Skin
Dry Skin
DermExcel™ | Dermdefence SPF 50: Trial

Shield against UVA, UVB, infrared, and blue light while moisturizing, minimizing redness, and preventing aging.
Dermdefence SPF 50: Trial

testimonials

Customer Reviews

Based on 805 reviews
94%
(760)
3%
(24)
2%
(15)
0%
(0)
1%
(6)
H
Hester Steyn
Dermatint

Lightweight very natural, not oily

E
Elize Van der merwe
Absolutely perfect!

I have been using this product for a while now. I’m 48 years old, and use this as a foundation. I have sensitive skin and rosacea, but everyone wants to know what my secret to beautiful skin is. I honoustly get a lot of compliments and it’s all thanx to Derm Excel!

L
Linda Nortier

Good and quick delivery

A
Antoinette Erasmus
Love the spf50

I have eczema and i get a allergic reaction to sunburn The best product to use on your face to prevent outbreak or a rash of the sun

D
Dorme Gertzen

Dermatint

S
Sheryl Eccleshare
Cleanser

Absolutely the best I have ever tried, and I have tried lots,
Makes my skin feels clean and soft

123
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