Name: Salicylic Gel
Brand: DermExcel™
SKU: DX-SG
Price: 794.00 ZAR
Availability: InStock

DermExcel™

Salicylic Gel

R 794.00

4.9 / 5.0 from 466 reviews

Pay interest-free installments from R 198.50 with various payment gateways selected at checkout.

SIZE: 30 mL

↓ Sebum

Unclog Pores

Anti-Acne

↓ inflammation

Ingrown hair

Salicylic Gel is a scientifically formulated chemical exfoliating treatment enriched with 5% Salicylic acid, renowned for its potent anti-inflammatory, oil-regulating, and cell-resurfacing properties. This advanced gel is meticulously designed to combat acne and folliculitis by effectively inhibiting the growth of acne-causing bacteria. It efficiently reduces irritation and inflammation associated with these conditions, relieving troubled skin.

With its optimal concentration of Salicylic acid, Salicylic Gel clears existing acne and folliculitis lesions, promoting a smoother and healthier complexion. By gently exfoliating the skin's surface, it aids in cell turnover, diminishing the appearance of blemishes and scars over time.

Featuring its primary active ingredient, Salicylic acid, this targeted gel provides a safe and reliable solution to tackle breakouts effectively. Regulating the skin's sebum production helps prevent future breakouts, addressing the root cause of acne and folliculitis. Salicylic Gel is a valuable addition to any skincare routine, particularly for those seeking a scientifically backed solution to troublesome skin conditions.

SHIPPING

Shipping Guarantee: Guiding you to healthy skin isn’t only about our products; it's also about getting them to you as swiftly as the science behind them. That's why Dermal Health offers a shipping guarantee you can rely on.
Where We Ship From: Orders are dispatched from our facilities in Pretoria.
Who We Ship With: We trust only well-known, popular, and dependable courier services with your packages.
When You'll Get It: Expect confident skin soon! Shipping addresses in Pretoria and Johannesburg will enjoy delivery from same-day to 2 business days. Shipping addresses further from Pretoria may expect delivery within 1-4 business days, depending on the service you select during checkout. Your estimated delivery date will reflect during checkout so that you can mark your calendar.
Tracking Your Order: Eager to start your DermExcel journey? We don't blame you! You'll receive a tracking number after you place your order so that you can follow your package.

For any shipping inquiries, our customer service team is ready to assist.

RETURNS

Dermal Health Science 30-Day Confidence Guarantee: We are passionate about guiding you to healthy skin through medical science. We believe in the quality and effectiveness of our products so much that we offer a 30-Day Confidence Guarantee.

If you're unsatisfied with your purchase, simply return it within 30 days for a full refund.

Healthy Skin Is Not Complicated and neither is our return policy. Please visit our detailed return policy or contact our friendly customer service team for more information.

Feel as confident in us as we want you to feel in your skin.

SECURE PAYMENT

If you're unsatisfied with your purchase, simply return it within 30 days for a full refund.

Healthy Skin Is Not Complicated and neither is our return policy. Please visit our detailed return policy or contact our friendly customer service team for more information.

Feel as confident in us as we want you to feel in your skin.

Salicylic Gel

R 794.00

Acne: Clear existing lesions and prevent future breakouts. Its anti-inflammatory action reduce redness and inflammation associated with acne, while its oil-regulating effects help control sebum production.
Folliculitis: Help manage the inflammation of hair follicles and inhibit the growth of bacteria that contribute to folliculitis.
Oily skin: Regulate and control excessive sebum production, reducing shine and helping prevent clogged pores.
Rough Skin Texture: Enhance skin smoothness, minimize roughness, and refine the appearance of pores, resulting in a more even and refined complexion.
Congested Pores: Oil soluble and, therefore, able to penetrate the pores to dissolve oil and cell debris to unclog pores.
Psoriasis: Soften and remove scales associated with psoriasis due to its keratolytic action.
Keratosis Pilaris: Reduce the appearance of rough, bumpy skin associated with this condition.

evening

Application time: Evening.
Frequency: 2-3 times per week as tolerated by your skin, or follow your Dermal Diagnosis treatment plan instructions. Once an affected area becomes clear, occasional use will maintain remission.

1. Cleanse

Start with clean and dry skin.
Use your DermExcel cleanser to remove dirt and excess oil from your skin.

2. Apply

Dispense a small amount of product onto your fingertips.
Apply evenly over your face or on body areas of concern.
Avoid sensitive areas, e.g., the eyes and lips.

Important note

Start by applying this exfoliator one evening per week. After one week, increase usage to two evenings a week.
Observe how your skin responds and adjust usage accordingly.
You may use this treatment every second night if you don't have sensitive skin.
Don't apply any other product to the area treated with your exfoliating treatment. The other product may alter the pH of the active ingredients, lowering the product's potency.
This exfoliating treatment promotes skin peeling by effectively removing dead skin cells. Peeling is a normal reaction and not a sign of skin dryness. You should notice decreased peeling as the product works to exfoliate dead skin.
You may notice a slight stickiness on your skin after applying your exfoliating product. This sensation is typical due to the hydroxyethylcellulose, a thickening agent that helps the treatment adhere to the skin. This allows the active ingredients to work effectively throughout the night by promoting exfoliation and cell turnover. Embrace this as a sign that the active ingredients are set to rejuvenate your skin while you sleep without the inconvenience of daytime residue.
Always use SPF 30 or greater during the day.

Active ingredients

Salicylic acid

Full Ingredient list

Aqua, Polyethylene Glycol, Ethoxydiglycol, Ethyl alcohol, Hydroxyethyl cellulose, Salicylic acid, Phenoxyethanol & Ethylhexylglycerin, Disodium EDTA

Salicylic Gel

product benefits

Targeted Acne Treatment

Promote cellular turnover, reduce pore congestion, eliminate acne-causing bacteria, and down-regulate inflammation, resulting in a smooth and healthy complexion.

Unblock clogged pores

Penetrate deeply into pores to dissolve excess sebum and debris, minimizing the risk of acne formation and enlarged pores.

Anti-Microbial

Manage microbial activity by inhibiting the growth of pathogenic bacteria, balancing the skin's microbiome, and reducing the risk of infections and inflammation.

Anti-inflammatory

Alleviates skin irritation and redness by targeting inflammatory pathways and markers, offering significant relief for inflamed skin conditions.

Improve Skin Texture

Smooth out uneven skin surfaces by promoting consistent cell turnover, reducing rough patches, and improving the skin's overall tactile and visual texture.

Minimize Pores

Remove excess oil and dead skin cells and improve skin texture to minimize the appearance of enlarged pores.

Indications for Salicylic Gel

Clogged Pores
Enlarged Pores
Shaving Bumps
ingrown hair
Folliculitis
Facial and Body Acne
Inflammation
blackheads
whiteheads
Seborrheic Dermatitis

Regulate sebum

Medical-grade treatment

Exfoliates dead skin cells

Unclog pores

Target acne and Blackheads

Salicylic Gel

salicylic acid targets all phases of the acne process

Unclog Pores

Salicylic acid is lipophilic, which means it can penetrate oily skin and clogged pores, resulting in deep cleaning.
Decongests pores by dissolving and extracting dirt, oil, and cellular debris in the pores and follicles.

Anti-Aging

Salicylic acid brightens the complexion. It acts as an exfoliant by softening and dissolving keratin, thus allowing dead skin cells to shed naturally.
Studies have indicated that salicylic acid's exfoliating properties reduce the appearance of fine lines and wrinkles. Over time, exfoliation helps to reduce the thickness of the layer of dead skin cells, giving the skin a brighter, more glowing appearance.

Regulate Sebum (oil)

Salicylic acid works well to balance sebum levels because it is lipid or oil-soluble. So, rather than remaining on the skin's surface, Salicylic acid penetrates deep into sebum-filled pores.

Microbial Control

It inhibits the production of various aspects necessary for bacterial reproduction, such as fibrinogen, fibronectin, and alpha-hemolysis. Therefore, salicylic acid may neutralize the bacteria C. acnes in blemishes.

anti-inflammatory & anti-acne

Salicylic acid reduces sebum secretion.
Salicylic acid has potent anti-inflammatory effects, inhibiting the arachidonic acid cascade.
Salicylic acid reduces inflammation by modulating COX2 gene expression to decrease the formation of pro-inflammatory cytokines.

Exfoliating

Salicylic acid works well to balance sebum levels because it is lipid or oil-soluble. So, rather than remaining on the skin's surface, Salicylic acid penetrates deep into sebum-filled pores.
Salicylic acid works by loosening and breaking apart desmosomes (attachments between cells in the outer layers of the skin). This action encourages the exfoliation of dead and damaged skin and unclogging pores.
Disrupts cellular junctions to exfoliate dead skin cells.

salicylic acid targets all phases of the acne process

Process

The first step in forming a blemish involves sebum, a naturally occurring oily substance that moisturizes, lubricates, and protects the skin and hair. While sebum production is normal, too much can lead to clogged pores.

______

Targeted treatment

Salicylic acid balances sebum levels because it is lipid or oil-soluble. So, rather than remaining on the skin's surface, salicylic acid penetrates deep into sebum-filled pores.

Sebum over-production

Process

The first step in forming a blemish involves sebum, a naturally occurring oily substance that moisturizes, lubricates, and protects the skin and hair. While sebum production is normal, too much can lead to clogged pores.

______

Targeted treatment

Salicylic acid balances sebum levels because it is lipid or oil-soluble. So, rather than remaining on the skin's surface, salicylic acid penetrates deep into sebum-filled pores.

Clogged pores

Process

The next step in the development of acne is triggered when the skin's follicles are not exfoliating properly. This means keratin, a protein found within the skin, and sebum clog the follicle.

______

Targeted treatment

Salicylic acid decongests pores by dissolving and extracting dirt, oil, and cellular debris in the pores and follicles.
Salicylic acid disrupts cellular junctions to exfoliate dead skin cells.

Bacterial infiltration

Process

When the follicle becomes clogged, a species of bacteria called Cutibacterium acnes (formerly Propionibacterium acnes) accumulates and multiplies in the follicle.

______

Targeted treatment

Salicylic acid inhibits the production of various aspects necessary for bacterial reproduction, such as fibrinogen, fibronectin, and alpha-hemolysis.

Inflammation

Process

After bacterial infiltration the follicle becomes inflamed, thus leading to pimple formation.

______

Targeted treatment

Salicylic acid suppresses pro-inflammatory cytokine expression.
Salicylic acid inhibits the arachidonic acid cascade.

FDA OTC Drug Monograph

Salicylic acid 3%

The US Food and Drug Administration (FDA) approves salicylic acid in OTC drug products.

In addition to being FDA-approved as a safe and effective acne drug, it is also approved for use in OTC drugs for corn, callus, wart removal, and anti-dandruff drug products.

FDA Category	Indication
CFR 21, 333.310	acne
CFR 21, 358.710 (b)	Seborrheic Dermatitis
CFR 21, 358.710 (c)	Psoriasis

the stages of acne

Regulate sebum (oil) production and secretion

The excretion of lipids by the sebaceous glands is controlled hormonally.
The sebaceous glands are located all over the body but are the largest and most numerous in the face, back, chest, and shoulders.
These glands become more active during puberty because of increased androgens, particularly testosterone, which spurs sebum production.
This imbalance between sebum production and secretion capacity leads to a blockage of sebum in the hair follicle, followed by inflammation.
Hormones continue to affect sebaceous gland activity into adulthood.

Prevent and remove content build-up in pores

The first stage of acne is called comedogenesis (formation of comedones).
The exfoliated dead skin cells stick together inside the hair follicle, resulting in a clogged pore or comedone.
This is caused by several factors, including increased amounts of sebum, inflammation of the sides of the hair follicle preventing the release of the exfoliated keratinocytes, and increased cohesion of keratinocytes.
Salicylic acid decongests pores by dissolving and extracting dirt, oil, and cellular debris (dead skin cells) in the pores and follicles.

Prevent Bacterial Infiltration and infection

The keratinocyte plug and sebum provide excellent food sources for bacteria.
The bacteria invade the comedone and release inflammatory factors that lead to the next stage of acne.
Salicylic acid inhibits the production of various aspects necessary for bacterial reproduction, such as fibrinogen, fibronectin, and alpha-hemolysis.

Down-regulate and prevent inflammation

Inflammation continues with increased redness and pus.
This is clinically detectable as a papule or pustule.
Continued inflammation may lead to so much inflammation that the hair follicle ruptures and the bacteria and debris are released into the dermis.
Salicylic acid suppresses pro-inflammatory cytokine expression.

Rosacea

Stages and treatment objectives

The skin, microorganisms and the environment constantly interact to maintain a delicate balance. Disturbance of this balance negatively influences both the microflora and skin health.

In Rosacea, the microenvironment of the affected skin is substantially altered, resulting in a shift in the proportion or speciation of the resident microflora. Several microorganisms are increased or immunoreactive if you struggle with rosacea.

Our skin contains pattern recognition receptors (PPR). These receptors detect harmful bacteria on our skin, bind to them, and activate an immune response.

Receptors (PPR) don't activate the immune response for normal micro-flora on our skin. Rosacea-prone skin receptors (PPR) are hyper-reactive and/or have decreased tolerance. They have heightened sensitivity and trigger the inflammatory response of normal microbes, leading to the initial signs of rosacea.

Healthy skin with a perfect balance between normal microflora and skin receptors.
Pathogen-recognizing receptors (PPR) detect and bind to harmful molecules, activating the immune response.
These receptors should not trigger an immune response by binding to normal microflora.

PPR (receptors) of Rosacea-prone skin bind to normal flora (they are not supposed to) and activate the immune response that causes inflammation.
PPR (receptors) of Rosacea-prone skin is hyper-reactive and sensitive. They can be activated by various environmental agents (fragrance, heat, spicy food, etc.)

Inflammation leads to an increase in white blood cells (leucocytes) and antimicrobial peptides (cathelicidins), causing certain normal microbes to be eliminated.
Disrupting the body's normal microbial community leads to an imbalance, where potentially harmful microbes overgrow and occupy spaces left by the eliminated beneficial microbes.

The negative feedback loop continues: Alterations in the micro-flora lead to increased inflammation, which in turn exacerbates Rosacea, resulting in more severe symptoms.

mode of action

salicylic acid

rosacea and acne treatment

anti-inflammatory

Inhibit the inflammation that leads to breakouts, redness, and skin damage.

Anti-bacterial

Inhibits bacteria responsible for causing and aggravating acne and rosacea.

Comedolytic

Unclog pores by dissolving and extracting dirt, oil, and cellular debris.

Keratolytic

Disrupts cellular junctions to exfoliate dead skin, revealing bright, new cells.

Testimonials

Overnight Miracle

I've been using the glycolic gel for almost a year now, and I am absolutely thrilled with the results! It's like an overnight miracle for my skin—every time I apply it, I wake up to smoother, more radiant skin. At first, it took a little time for my face to adjust, but once it did, there was no turning back. I highly recommend it. 5/5 from me!

Glycolig Gel

Love love love!!! Saw a difference after 2 weeks!

Love this product.

Makes my skin super smooth and soft.

Excellent

There is no product better than Dermalhealth.

Awesome Glycolic Gel

Dermexcel’s Glycolic Gel is my goto night treatment. I love how my skin looks and feels when I wake up.

T zone breakouts

Bought for my teen son. And unfortunately we cannot see that his breakouts are clearing up in anyway
I will give it some more time though

1 2 3

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Salicylic Gel

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Targeted treatment

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Targeted treatment

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Targeted treatment

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Targeted treatment

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Targeted treatment

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Targeted treatment

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Targeted treatment

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Targeted treatment

mode of action

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