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Follicure Follicure Follicure Follicure

Follicure


SIZE: 120 mL

healthy scalp

healthy scalp

anti-dundruff

anti-dundruff

↓ inflammation

↓ inflammation

oil control

oil control

Itch Relief

Itch Relief


A maximum strength medicated scalp treatment to relieve itching, irritation, redness, flaking, and scaling associated with dandruff and seborrheic dermatitis.

A powerful formula that combines 2% Salicylic acid and 2% Zinc pyrithione for maximum effectiveness and life-changing results.

Our advanced formulation is enriched with Ceramides, fatty acids, and Cholesterol, intelligently combining to repair, strengthen, and revive the skin barrier. This powerhouse blend of potent ingredients supports the dermis in retaining moisture, preventing water loss, and restoring the skin structure, resulting in a healthier, more vibrant complexion.

Zinc Pyrithione, an antifungal, antimicrobial, and antibacterial agent, works by reducing the amount of fungus that triggers inflammation and scaling. Zinc Pyrithione also treats pityrosporum folliculitis (fungal acne) on the face and other body parts.

Salicylic acid gently exfoliates the scalp, removing dead skin cells and excess oil, contributing to dandruff and itchiness. As a result, it unclogs hair follicles, promoting a healthier scalp environment.


Zinc Pyrithione

Zinc pyrithione, a compound with potent antifungal and antibacterial properties, has established itself as a cornerstone in the treatment of various skin conditions, particularly those involving Malassezia yeast. Its effectiveness against seborrheic dermatitis and dandruff, which are often associated with an overgrowth of Malassezia species, makes it a key ingredient for many dermatological conditions.

Zinc pyrithione’s mode of action is multifaceted, primarily targeting the membrane of fungi and bacteria, thereby disrupting their growth and replication. One of its significant mechanisms involves inhibiting fungal cell membrane transport by blocking the energy production pathway, which is crucial for cell survival.

In Malassezia, yeast, a natural inhabitant of the skin flora, can overgrow and cause conditions like seborrheic dermatitis and dandruff; zinc pyrithione's antifungal action is particularly beneficial. It reduces the yeast population on the skin, thereby alleviating the symptoms associated with its overgrowth, such as flaking, irritation, and redness.

Its efficacy in treating seborrheic dermatitis is attributed to its ability to reduce the Malassezia count, diminish inflammatory responses, and soothe the skin. Similarly, in dandruff, which is often linked to an excess of Malassezia, zinc pyrithione effectively reduces flaking and itchiness, promoting a healthier scalp environment.

The efficacy of zinc pyrithione in the treatment of seborrheic dermatitis and dandruff is well-documented. Its safety profile and efficacy have been confirmed by numerous studies, with significant improvements observed in both scalp and skin conditions following regular use.


Physiological Effects

  • Antifungal Activity: It is effective against a range of fungi, including those that cause dandruff and seborrheic dermatitis. Zinc Pyrithione inhibits the division of fungal cells, reducing their proliferation.
  • Antibacterial Properties: This compound also exhibits antibacterial activity, making it useful in treating and preventing bacterial skin infections.
  • Anti-inflammatory Effects: Zinc Pyrithione can reduce inflammation, which is beneficial in alleviating symptoms of various inflammatory skin conditions.
  • Sebum Regulation: It helps in regulating sebum production, which can be beneficial for oily skin and conditions like acne.

Role in Managing Dermatological Conditions

  • Dandruff and Seborrheic Dermatitis: Zinc Pyrithione is a common ingredient in anti-dandruff shampoos and is effective in controlling the flaking and itching associated with these conditions.
  • Psoriasis: It can help manage the symptoms of psoriasis, particularly in reducing scaling and redness.
  • Acne: Due to its antibacterial and anti-inflammatory properties, Zinc Pyrithione can be beneficial in the treatment of acne.
  • Fungal Infections: It is effective in treating various fungal skin infections due to its antifungal properties.

References

  • Warshaw, E. M., et al. (2005). Efficacy of Zinc Pyrithione in Seborrheic Dermatitis and Dandruff. Dermatology.
  • Pierard-Franchimont, C., et al. (2002). Antidandruff shampoo efficacy in dandruff/seborrhoeic dermatitis. International Journal of Cosmetic Science.
  • Scheman, A., et al. (2000). Antimicrobial Activity of Zinc Pyrithione. American Journal of Infection Control.
Salicylic Acid

Salicylic acid, a renowned beta hydroxy acid (BHA), is a cornerstone in dermatology and skincare due to its exceptional keratolytic and comedolytic properties. Its unique ability to penetrate oil-laden hair follicle pores makes it particularly effective in treating acne-prone and oily skin types.

Salicylic acid dissolves skin debris (sebum and dead skin cells) that clogs pores and causes acne. It's a mild antibacterial and powerful anti-inflammatory agent that helps reduce the redness and swelling associated with breakouts.

What sets salicylic acid apart in dermatological treatments is its ability to exfoliate the skin, not just on the surface but within the pores themselves. This is due to its oil-soluble nature, which allows it to penetrate deep into the pores and dissolve the keratin plugs that lead to blackheads and whiteheads.

Furthermore, salicylic acid also has the capacity to adjust the pH of the skin, creating an environment less favorable for the growth of acne-causing bacteria. Salicylic acid's efficacy in treating various skin conditions, particularly acne, has been extensively documented in the scientific literature. Studies have consistently shown its ability to reduce acne lesions in terms of count and severity. Additionally, salicylic acid is highly recommended for its effectiveness in treating other skin conditions, such as psoriasis and dandruff, due to its ability to soften and remove scales and flakes from the skin.


Physiological Effects

  • Keratolytic Action: Salicylic acid is known for its ability to exfoliate the skin by dissolving the intercellular 'glue' that holds skin cells together, helping to remove dead skin cells and unclog pores.
  • Comedolytic Effect: It is particularly effective in reducing comedones (blackheads and whiteheads) by unclogging pores and preventing the formation of new comedones.
  • Anti-inflammatory Properties: Salicylic acid reduces inflammation, which is beneficial in treating acne and other inflammatory skin conditions.
  • Sebum Regulation: It helps to regulate oil production, making it a valuable ingredient for managing oily and acne-prone skin.
  • Penetration Enhancement: Due to its lipophilic nature, it can penetrate sebum-filled follicles, effectively treating acne located deep within the pores.

Role in Managing Dermatological Conditions

  • Acne Vulgaris: Salicylic acid is a cornerstone in acne treatment, effectively preventing and treating existing acne lesions.
  • Psoriasis: Its keratolytic properties make it helpful in softening and removing scales associated with psoriasis.
  • Warts: Salicylic acid is commonly used to treat warts because it can exfoliate and remove the thickened skin.
  • Seborrheic Dermatitis: It helps manage seborrheic dermatitis by reducing scaling and redness.
  • Keratosis Pilaris: Salicylic acid can aid in smoothing the rough bumps associated with keratosis pilaris.

References

  • Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., & Thiboutot, D. M. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973.e33.
  • Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, cosmetic and investigational dermatology, 3, 135.
  • Zander, E., & Weisman, S. (1992). Treatment of acne vulgaris with salicylic acid pads. Clinical Therapeutics.
  • Gupta, A. K., & Nicol, K. (2004). The use of sulfur in dermatology. Journal of Drugs in Dermatology.

Free Gift with Follicure:
Mini Silicone Scalp Massager
Mini Silicone Scalp Massager
DermExcel™ | Follicure
Follicure Sale priceR 497.00
  • Dandruff
  • Seborrheic dermatitis
  • Itchy and irritated scalp
  • Inflammation
  • Acne, body acne and conditions related to yeast / fungal infections
  • Shaving bumps / Folliculitis
  • Psoriasis

Active ingredients

    Zinc Pyrithione

    Salicylic acid, a renowned beta hydroxy acid (BHA), is a cornerstone in dermatology and skincare due to its exceptional keratolytic and comedolytic properties. Its unique ability to penetrate oil-laden hair follicle pores makes it particularly effective in treating acne-prone and oily skin types.

    Salicylic acid dissolves skin debris (sebum and dead skin cells) that clogs pores and causes acne. It's a mild antibacterial and powerful anti-inflammatory agent that helps reduce the redness and swelling associated with breakouts.

    What sets salicylic acid apart in dermatological treatments is its ability to exfoliate the skin, not just on the surface but within the pores themselves. This is due to its oil-soluble nature, which allows it to penetrate deep into the pores and dissolve the keratin plugs that lead to blackheads and whiteheads.

    Furthermore, salicylic acid also has the capacity to adjust the pH of the skin, creating an environment less favorable for the growth of acne-causing bacteria. Salicylic acid's efficacy in treating various skin conditions, particularly acne, has been extensively documented in the scientific literature. Studies have consistently shown its ability to reduce acne lesions in terms of count and severity. Additionally, salicylic acid is highly recommended for its effectiveness in treating other skin conditions, such as psoriasis and dandruff, due to its ability to soften and remove scales and flakes from the skin.


    • Keratolytic Action: Salicylic acid is known for its ability to exfoliate the skin by dissolving the intercellular 'glue' that holds skin cells together, helping to remove dead skin cells and unclog pores.
    • Comedolytic Effect: It is particularly effective in reducing comedones (blackheads and whiteheads) by unclogging pores and preventing the formation of new comedones.
    • Anti-inflammatory Properties: Salicylic acid reduces inflammation, which is beneficial in treating acne and other inflammatory skin conditions.
    • Sebum Regulation: It helps to regulate oil production, making it a valuable ingredient for managing oily and acne-prone skin.
    • Penetration Enhancement: Due to its lipophilic nature, it can penetrate sebum-filled follicles, effectively treating acne located deep within the pores.

    • Acne Vulgaris: Salicylic acid is a cornerstone in acne treatment, effectively preventing and treating existing acne lesions.
    • Psoriasis: Its keratolytic properties make it helpful in softening and removing scales associated with psoriasis.
    • Warts: Salicylic acid is commonly used to treat warts because it can exfoliate and remove the thickened skin.
    • Seborrheic Dermatitis: It helps manage seborrheic dermatitis by reducing scaling and redness.
    • Keratosis Pilaris: Salicylic acid can aid in smoothing the rough bumps associated with keratosis pilaris.

    • Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., & Thiboutot, D. M. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973.e33.
    • Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, cosmetic and investigational dermatology, 3, 135.
    • Zander, E., & Weisman, S. (1992). Treatment of acne vulgaris with salicylic acid pads. Clinical Therapeutics.
    • Gupta, A. K., & Nicol, K. (2004). The use of sulfur in dermatology. Journal of Drugs in Dermatology.
    Salicylic Acid

    Salicylic acid, a renowned beta hydroxy acid (BHA), is a cornerstone in dermatology and skincare due to its exceptional keratolytic and comedolytic properties. Its unique ability to penetrate oil-laden hair follicle pores makes it particularly effective in treating acne-prone and oily skin types.

    Salicylic acid dissolves skin debris (sebum and dead skin cells) that clogs pores and causes acne. It's a mild antibacterial and powerful anti-inflammatory agent that helps reduce the redness and swelling associated with breakouts.

    What sets salicylic acid apart in dermatological treatments is its ability to exfoliate the skin, not just on the surface but within the pores themselves. This is due to its oil-soluble nature, which allows it to penetrate deep into the pores and dissolve the keratin plugs that lead to blackheads and whiteheads.

    Furthermore, salicylic acid also has the capacity to adjust the pH of the skin, creating an environment less favorable for the growth of acne-causing bacteria. Salicylic acid's efficacy in treating various skin conditions, particularly acne, has been extensively documented in the scientific literature. Studies have consistently shown its ability to reduce acne lesions in terms of count and severity. Additionally, salicylic acid is highly recommended for its effectiveness in treating other skin conditions, such as psoriasis and dandruff, due to its ability to soften and remove scales and flakes from the skin.


    • Keratolytic Action: Salicylic acid is known for its ability to exfoliate the skin by dissolving the intercellular 'glue' that holds skin cells together, helping to remove dead skin cells and unclog pores.
    • Comedolytic Effect: It is particularly effective in reducing comedones (blackheads and whiteheads) by unclogging pores and preventing the formation of new comedones.
    • Anti-inflammatory Properties: Salicylic acid reduces inflammation, which is beneficial in treating acne and other inflammatory skin conditions.
    • Sebum Regulation: It helps to regulate oil production, making it a valuable ingredient for managing oily and acne-prone skin.
    • Penetration Enhancement: Due to its lipophilic nature, it can penetrate sebum-filled follicles, effectively treating acne located deep within the pores.

    • Acne Vulgaris: Salicylic acid is a cornerstone in acne treatment, effectively preventing and treating existing acne lesions.
    • Psoriasis: Its keratolytic properties make it helpful in softening and removing scales associated with psoriasis.
    • Warts: Salicylic acid is commonly used to treat warts because it can exfoliate and remove the thickened skin.
    • Seborrheic Dermatitis: It helps manage seborrheic dermatitis by reducing scaling and redness.
    • Keratosis Pilaris: Salicylic acid can aid in smoothing the rough bumps associated with keratosis pilaris.

    • Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., & Thiboutot, D. M. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973.e33.
    • Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, cosmetic and investigational dermatology, 3, 135.
    • Zander, E., & Weisman, S. (1992). Treatment of acne vulgaris with salicylic acid pads. Clinical Therapeutics.
    • Gupta, A. K., & Nicol, K. (2004). The use of sulfur in dermatology. Journal of Drugs in Dermatology.

Full ingredient list

    Aqua, Polyethylene Glycol, Coco-Glucoside, Cocoamidopropyl Betaine, Sodium Lauroyl Sarcosinate, Salicylic acid, Zinc Pyrithione, Phenoxyethanol & Ethyl hexyl Glycerin, Acrylates Copolymer, Triethanolamine, Coco-Glucoside & Glyceryl Oleate

Evening

  • Active Scalp Treatment: Apply Follicure 2 to 3 times per week, depending on the severity of your condition. As your symptoms improve, you may reduce the frequency of use.
  • Healthy Scalp Maintenance: Apply Follicure to affected or previously affected areas at least once weekly.

1. Apply

Apply to wet hair and scalp
  • Wet hair allows the product to distribute evenly and work effectively on the scalp.
  • Take a sufficient amount of Follicure and gently massage it onto the wet scalp, ensuring complete coverage.
  • Pay particular attention to areas with visible signs of dandruff, itchiness, or irritation.

2. Massage into scalp

  • Use the fingertips or the included scalp massager to massage Follicure into the scalp with circular motions. This helps to activate the ingredients and promotes better penetration.
  • Leave Follicure on the scalp for approximately 5 to 10 minutes to allow the active ingredients to work effectively.

3. Rinse

  • After the designated time, thoroughly rinse hair and scalp with lukewarm water, ensuring that all residue is removed.
  • It is important to rinse thoroughly, as any remaining product on the scalp may cause irritation or reduce the effectiveness of the treatment.

Usage Frequency

  • Apply Follicure 2 to 3 times per week, depending on the severity of your condition. As your symptoms improve, you may reduce the frequency of use.
  • To ensure healthy skin maintenance, apply Follicure to affected areas at least once per week.

Follicure

product benefits

Keratolytic action
Keratolytic action

Exfoliate dead skin cells that accumulate and become trapped in hair follicles. This leads to the overgrowth of dandruff, which causes Malassezia yeast.

Sebum (oil) regulation
Sebum (oil) regulation

Sebum is an oily substance produced by the sebaceous glands on the scalp. When it is overproduced, it contributes to the development of dandruff.

Anti-Inflammatory
Anti-Inflammatory

Reduces inflammation associated with acne and folliculitis. It helps soothe irritated skin, alleviating redness and discomfort.

Anti-fungal action
Anti-fungal action

Disrupt the cell membrane of the dandruff-causing Malassezia yeast, which inhibits its growth and reduces its ability to colonize the scalp.

follicure

mode of action

Cleansers

testimonials

Customer Reviews

Based on 792 reviews
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Customer
In-house Salon

This range of products are the best. It's like having a salon treatment in the comfort of your own home every day. Would recommend it to all

E
Eloise Schutte
Pore Control Cleanser

Absolutely love this product! I will never use anything other than this cleanser ever again! I have struggled with my skin for many years, and tried various products. This cleanser cleans, refreshes, moisturize and tightens pores.

E
Estelle De bruyn
Happiness in a bottle

Best decision i ever made was to change my skincare to dermexcel.

L
L. N
Pore control cleanser

Just loving my cleanser

L
Lufuno Ndou

Renewal Facial Cleanser

m
moniek de Rooy
Great products

I absolutely love my products and can see a change in my skin as I am in the over 40 ‘s club and need a bit of extra help.
Amazing ! Thanks

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