DermExcel™ | New DermExceller

Ready to Experience the DermExcel Difference?

Embarking on Your DermExcel Journey to Confident Skin

Starting a new skincare regimen is a powerful step toward healthier, more confident skin, and we’re excited to share this journey with you!

DermExcel’s multi-active ingredient formulations are designed to deliver transformative, visible results. As with any highly effective, medical-grade skincare, you may experience some initial adjustments—dryness, flaking, mild redness, or a slight stinging sensation. These are all common signs that your skin is responding to active ingredients and initiating the renewal process.

To help you feel confident as you start, we’ll guide you through what to expect, how to manage these early signs of skin adjustment, and provide tips to keep your skin balanced, calm, and comfortable during the transition.

why do skin reactions happen?

DermExcel’s pharmaceutical-grade skincare products are formulated with advanced delivery systems designed to deliver active ingredients deeply within the skin, reaching receptor sites located in the dermal layers. This targeted penetration is crucial for facilitating effective cellular communication and maximizing the effectiveness of each ingredient. Unlike over-the-counter skincare, which often remains on the skin’s surface, DermExcel’s formulations are designed to work at a deeper level, where skin renewal and repair occur.

Due to this enhanced delivery, our products can be more potent than typical consumer-grade skincare, which may lead to an initial reaction as your skin adjusts. Reactions such as dryness, flaking, or redness occur as active ingredients begin to stimulate skin renewal processes, encouraging cell turnover and collagen synthesis. These early adjustments indicate that your skin is responding to the multi-active components, laying the groundwork for healthier, revitalized skin over time.

As your skin continues to acclimate, these initial responses generally subside, allowing you to experience the transformative benefits of DermExcel’s formulations. Gradually, you’ll notice visible improvements in texture, tone, and resilience, reflecting the cumulative impact of potent, well-supported active ingredients working in harmony with your skin.

Skin Reactions vs. Allergic Reactions

When starting with DermExcel’s advanced, medical-grade formulations, it’s common to experience initial reactions such as mild dryness, flaking, purging, redness, or a light stinging sensation. These responses result from our carefully calibrated, pharmaceutical-grade active ingredients, selected for their effectiveness and balanced at optimal pH levels to support skin renewal and rejuvenation. As these actives penetrate the skin’s dermal layers, they initiate a renewal process that may involve temporary adjustments as your skin acclimates.

However, differentiating between expected reactions and potential allergic responses is essential. While normal adjustments should gradually ease as your skin becomes accustomed, allergic reactions tend to involve more intense or prolonged symptoms, such as persistent redness, sustained stinging, hives, or noticeable swelling. The DermExcel products are formulated to minimize these risks—they’re free from added oils, sulfates, fragrance, and common allergens, making true allergies extremely rare.

If you’re uncertain whether what you’re experiencing is part of the normal adjustment or an allergic response, don’t hesitate to reach out to our clinical advisors. They’re here to provide expert guidance and help you determine the best course of action. And, if severe or persistent symptoms arise that don’t improve within a few days after discontinuing use—or if over-the-counter remedies don’t bring relief—consulting your medical practitioner is advised.

Timelines for Visible Results

When beginning a new skincare regimen, it’s normal for improvements—especially in breakouts and texture—to take around eight weeks to become visible. This timeframe allows DermExcel’s active ingredients to work through several skin renewal cycles, progressively reducing acne, refining texture, and addressing other concerns.

For hyperpigmentation, however, patience is key, as these results can take longer to emerge. Fading pigmentation depends on factors such as severity, depth, and cause, as pigmentation lies within the deeper skin layers. Consistent treatment over multiple cell turnover cycles is required to inhibit melanin production and reach these deeper layers, making steady, dedicated use essential for lasting improvements.

Sometimes, a simple tweak in your regimen can help you achieve optimal results. If you’re not seeing the progress you anticipated, our clinical advisors are available to offer personalized recommendations based on your skin’s specific needs. DermExcel offers potent chemical exfoliating products that enable at-home chemical peels, providing you with powerful tools for deeper rejuvenation. Additionally, for those seeking faster progress, professional chemical peels from an aesthetic practitioner contain higher concentrations of active ingredients, which can help accelerate your treatment outcomes. Incorporating regular professional chemical peels into your routine can be a valuable addition, depending on your skincare goals.

why do skin reactions happen?

Skin Reactions vs. Allergic Reactions

Timelines for Visible Results

Managing common reactions

Purging: Initial Breakouts

A Natural Response to Active Ingredients

Starting active ingredients in your skincare can sometimes lead to an increase in breakouts, known as "purging." This is common with ingredients like AHAs, BHAs, and retinoids, which accelerate skin cell turnover, bringing trapped sebum, clogged pores, and impurities to the surface more quickly than usual.

It’s helpful to remember that pimples don’t form overnight. A breakout typically starts as a clogged pore that takes weeks to surface. By speeding up cell turnover, these actives bring underlying blemishes to the surface sooner, often causing a temporary increase in visible pimples.

While purging with AHAs and BHAs generally resolves within 2-4 weeks and may last 4-6 weeks with retinoids, each skin type is unique. Factors like skin sensitivity, previous skincare history, and environmental factors can influence the intensity and duration of purging.

During this period, consistency is key. If you continue with the recommended usage, the purging phase will pass, and your skin will reveal a clearer, healthier complexion.

Redness: Initial Flush

Understanding the Benefits Behind the Initial Flush

Initial redness is a typical response, often a sign that active ingredients are stimulating beneficial processes within your skin. Here’s how these processes work:

Enhanced Lymphatic Drainage: Active ingredients stimulate lymphatic drainage, promoting detoxification by removing toxins and impurities. This cleansing process helps clear out impurities from within, setting the foundation for healthier skin.
Increased Blood Flow: Redness often results from increased blood flow, which delivers oxygen-rich blood to the skin cells, thereby enhancing cellular health and radiance. It’s a natural skin response that supports collagen synthesis, cellular energy, and even skin tone over time. This improved circulation ultimately strengthens your skin’s resilience, contributing to long-term firmness and elasticity.
Accelerated Cell Turnover: Active ingredients speed up the turnover of skin cells, helping reveal a refined, more even texture.

As your skin adjusts to increased oxygenation and cellular activity, its resilience and ability to retain a healthy glow strengthen over time. This initial redness signals the beginning of long-term benefits, such as enhanced firmness and a naturally radiant tone.

Dryness and Flaking Skin

Understanding the Benefits and the Process

Dryness and flaking indicate that dead or damaged cells are shedding, making way for new skin. This exfoliation process is crucial for cellular turnover, enabling active ingredients to work more effectively. DermExcel’s serums, formulated to penetrate deeply, recalibrate the skin’s moisture balance, promoting natural hydration and effectively treating concerns like acne, aging, rosacea, pigmentation, etc.

Chemical Exfoliants: Ingredients like Salicylic Acid (a BHA) and Glycolic Acid (an AHA) play crucial roles in renewing the skin. Salicylic acid penetrates pores to clear sebum and impurities, while glycolic acid exfoliates the skin’s surface, refining texture and brightening tone.

Temporary dryness or flaking is a sign these actives are working as intended. Avoid picking at peeling skin; instead, gently lift any flaking with a microfiber cloth or lukewarm facecloth.

As DermExcel products recalibrate your skin’s hydration balance, you may notice a decrease in dryness and flaking over time. This recalibration reinforces your skin’s natural barrier, resulting in improved moisture retention and a long-lasting glow that requires fewer external moisturizers.

If dryness persists beyond 6 weeks, consider adding a DermExcel-recommended moisturizer for extra hydration.

Stinging and Burning

The mild stinging sensation you may feel when applying DermExcel products is a natural sign of the potency and effectiveness of our formulations. Unlike many skincare products on the market, which often include fillers to create a soft, soothing feel, DermExcel is free from these dilutive ingredients. Fillers can create a “feel-good” effect on the skin, but often reduce the concentration and impact of active ingredients, limiting results.

DermExcel formulations are crafted without fillers, ensuring that each product delivers a full strength of active, science-backed ingredients directly to your skin. This focused approach means that, especially during the initial applications, a slight stinging sensation is normal and expected. It’s a signal that the active ingredients are penetrating effectively and beginning their targeted work within the skin. As your skin adapts to these potent formulations, this sensation typically lessens, while the benefits of the actives continue to grow, helping reveal healthty and engergized skin.

For products containing Salicylic Acid and Glycolic Acid, a lower pH level is essential. This acidity optimizes their ability to penetrate the skin, dissolve dead skin cells, and clear congested pores, making these ingredients highly effective in addressing concerns like acne, pigmentation, and uneven texture. However, this lower pH can sometimes cause mild stinging or tingling as your skin adjusts to the active regimen. This sensation usually fades as your skin builds tolerance but is an indication that the acids are actively working to promote cell turnover.

Finding the right balance with active ingredients is key. While mild stinging is normal, prolonged burning or discomfort may indicate that your skin needs a gentler approach. If you experience ongoing sensitivity, try these adjustments to help your skin recover and gradually build tolerance:

Cleansers: Use once daily, applying with damp fingers to reduce potency. Rinse promptly after application.
Serums: Start every second or third day to allow your skin to build tolerance.
Exfoliators: Take a 1-2 week break, then reintroduce gradually.
DermExcel Moisturizers: Apply as needed to soothe and calm your skin.

As tolerance builds, you can increase usage per the product’s instructions.