DermExcel™

Glycolic Gel: Trial

Name: Glycolic Gel: Trial
Brand: DermExcel™
SKU: DX-GG05
Price: 124.35 ZAR
Availability: InStock

4.9 / 5.0 from 464 reviews

R 124.35

SIZE: 5 mL

Even Skin Tone

Anti-Aging

Brightening

Exfoliating

smooth skin

A high-potency exfoliating treatment formulated with 10% Glycolic acid at an optimal pH level. This scientifically developed formulation chemically exfoliates the epidermis, removing dull and dead skin cells to reveal a brighter, youthful complexion beneath. This treatment fortifies the skin by stimulating collagen production and enhancing skin hydration, providing structure and elasticity to the skin. Increasing cell turnover also supports the skin's natural repair mechanisms, contributing to overall skin health and youthful appearance.

Glycolic Gel’s anti-inflammatory properties reduce skin redness and improve skin texture, aiding in treating congested or acne-prone skin.

As a potent solution for at-home chemical peeling, addressing prevalent signs of aging, and optimizing skin health, Glycolic Gel is a testament to the power of science in skincare, offering tangible benefits while being easy to incorporate into a regular skincare regimen.

Glycolic acid

Glycolic acid is highly acclaimed for its remarkable exfoliating and rejuvenating properties. Its small molecular size enables deep skin penetration, fostering efficient exfoliation at the cellular level.

Glycolic acid’s water solubility allows it to penetrate the upper layers of the skin easily. Its primary mechanism of action involves weakening the bonds between dead skin cells, promoting their shedding, and revealing the newer, healthier skin beneath. This process of accelerated cell turnover is instrumental in addressing a range of skin concerns, from aging signs like fine lines and wrinkles to texture irregularities and hyperpigmentation.

Glycolic acid's efficacy extends beyond mere exfoliation. It's also recognized for stimulating collagen production, a crucial protein in maintaining skin's elasticity and firmness. This aspect contributes to its anti-aging benefits. Furthermore, its hydrating properties add to its appeal, as they help increase the skin's capacity to retain moisture, leading to a more supple and vibrant complexion.

Clinical studies have consistently supported glycolic acid's role in improving skin appearance. Research indicates significant improvements in skin texture and pigmentation and the visible reduction of wrinkles and fine lines with glycolic acid.

Physiological Effects

Exfoliation: Glycolic acid is a powerful exfoliant. It dissolves the bonds between dead skin cells on the skin’s surface, facilitating their removal and revealing newer, healthier skin underneath.
Increased Collagen Production: It stimulates collagen production, which is essential for skin elasticity and firmness. This action helps reduce the appearance of fine lines and wrinkles.
Enhanced Skin Hydration: Glycolic acid improves the skin's ability to retain moisture, enhancing hydration and a more plump, vibrant skin appearance.
Skin Brightening: Removing dead skin cells can brighten the complexion and reduce the appearance of dark spots and hyperpigmentation.
Improved Skin Texture: Regular use of glycolic acid can lead to smoother, more even textured skin, making it beneficial for conditions like keratosis pilaris.
Acne Treatment: Its exfoliating properties help in unclogging pores, thereby reducing the occurrence of acne breakouts.

Role in Managing Dermatological Conditions

Aging Skin: Glycolic acid is widely used in anti-aging products to reduce signs of aging, such as fine lines, wrinkles, and age spots.
Acne-Prone Skin: It helps manage acne by exfoliating the skin and removing blockage from pores.
Hyperpigmentation: It effectively treats hyperpigmentation by accelerating the removal of hyperpigmented skin cells.
Textural Irregularities: Glycolic acid can improve skin texture and is beneficial for treating keratosis pilaris and other conditions of rough skin.
Sun-Damaged Skin: It helps rejuvenate sun-damaged skin by accelerating cell turnover and collagen synthesis.

References

Bernstein, E. F. (2001). Glycolic acid treatment increases type I collagen mRNA and hyaluronic acid content of human skin. Dermatologic Surgery.
Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology.
Sharad, J. (2013). Glycolic acid peel therapy – a current review. Clinical, Cosmetic and Investigational Dermatology.
Smith, W. P. (1996). Epidermal and dermal effects of topical lactic acid. Journal of the American Academy of Dermatology, 35(3), 388-391.

USE DURING PREGNANCY

Glycolic Gel: Trial

SHIPPING

Shipping Guarantee: Guiding you to healthy skin isn’t only about our products; it's also about getting them to you as swiftly as the science behind them. That's why Dermal Health offers a shipping guarantee you can rely on.
Where We Ship From: Orders are dispatched from our facilities in Pretoria.
Who We Ship With: We trust only well-known, popular, and dependable courier services with your packages.
When You'll Get It: Expect confident skin soon! Shipping addresses in Pretoria and Johannesburg will enjoy delivery from same-day to 2 business days. Shipping addresses further from Pretoria may expect delivery within 1-4 business days, depending on the service you select during checkout. Your estimated delivery date will reflect during checkout so that you can mark your calendar.
Tracking Your Order: Eager to start your DermExcel journey? We don't blame you! You'll receive a tracking number after you place your order so that you can follow your package.

For any shipping inquiries, our customer service team is ready to assist.

RETURNS

Dermal Health Science 30-Day Confidence Guarantee: We are passionate about guiding you to healthy skin through medical science. We believe in the quality and effectiveness of our products so much that we offer a 30-Day Confidence Guarantee.

If you're unsatisfied with your purchase, simply return it within 30 days for a full refund.

Healthy Skin Is Not Complicated and neither is our return policy. Please visit our detailed return policy or contact our friendly customer service team for more information.

Feel as confident in us as we want you to feel in your skin.

SECURE PAYMENT

Dermal Health Science 30-Day Confidence Guarantee: We are passionate about guiding you to healthy skin through medical science. We believe in the quality and effectiveness of our products so much that we offer a 30-Day Confidence Guarantee.

If you're unsatisfied with your purchase, simply return it within 30 days for a full refund.

Healthy Skin Is Not Complicated and neither is our return policy. Please visit our detailed return policy or contact our friendly customer service team for more information.

Feel as confident in us as we want you to feel in your skin.

Aging Skin: Glycolic Gel targets signs of aging, including sagging skin and wrinkles. It can stimulate collagen production, leading to firmer skin over time.
Uneven Skin Tone: Brightens and evens the complexion for a more radiant look. It can stimulate collagen production, leading to firmer skin over time.
Sun-Damaged Skin: Aid in reducing visible signs of sun damage such as hyperpigmentation, uneven skin tone, and textural irregularities. vitality and improves the skin's overall radiance.
Dryness: Provides deep hydration, moisturizing the skin for a plumper and smoother texture.
Dull and Lifeless skin: Exfoliates dead skin cells, revealing a brighter and more radiant complexion underneath.
Uneven Skin Texture: Improve skin texture and tone, giving the skin a smoother and more uniform appearance.
Congested Pores: Glycolic Gel penetrates the skin to unclog pores.
Hyperpigmentation: Reduces melanin production, leading to a more even skin tone.
Overall Skin Health: Rejuvenates the skin, promoting a healthier and youthful complexion.

Evening

Application time: Evening.
Frequency: Once per week, up-titrating frequency of use as tolerated.

1. Cleanse

Start with clean and dry skin.
Use your DermExcel cleanser to remove dirt and excess oil from your skin.

2: Apply

Dispense a small amount of product onto your fingertips.
Apply evenly over your face or on body areas of concern.
Avoid sensitive areas, e.g., the eyes and lips.

Important note

Start by applying this exfoliator one evening per week. After one week, increase usage to two evenings a week.
Observe how your skin responds and adjust usage accordingly.
You may use this treatment every second night if you don't have sensitive skin.
Don't apply any other product to the area treated with your exfoliating treatment. The other product may alter the pH of the active ingredients, lowering the product's potency.
This exfoliating treatment promotes skin peeling by effectively removing dead skin cells. Peeling is a normal reaction and not a sign of skin dryness. You should notice decreased peeling as the product works to exfoliate dead skin.
You may notice a slight stickiness on your skin after applying your exfoliating product. This sensation is typical due to the hydroxyethylcellulose, a thickening agent that helps the treatment adhere to the skin. This allows the active ingredients to work effectively throughout the night by promoting exfoliation and cell turnover. Embrace this as a sign that the active ingredients are set to rejuvenate your skin while you sleep without the inconvenience of daytime residue.
Always use SPF 30 or greater during the day.

Active ingredients

Glycolic acid

Glycolic acid is highly acclaimed for its remarkable exfoliating and rejuvenating properties. Its small molecular size enables deep skin penetration, fostering efficient exfoliation at the cellular level.

Glycolic acid’s water solubility allows it to penetrate the upper layers of the skin easily. Its primary mechanism of action involves weakening the bonds between dead skin cells, promoting their shedding, and revealing the newer, healthier skin beneath. This process of accelerated cell turnover is instrumental in addressing a range of skin concerns, from aging signs like fine lines and wrinkles to texture irregularities and hyperpigmentation.

Glycolic acid's efficacy extends beyond mere exfoliation. It's also recognized for stimulating collagen production, a crucial protein in maintaining skin's elasticity and firmness. This aspect contributes to its anti-aging benefits. Furthermore, its hydrating properties add to its appeal, as they help increase the skin's capacity to retain moisture, leading to a more supple and vibrant complexion.

Clinical studies have consistently supported glycolic acid's role in improving skin appearance. Research indicates significant improvements in skin texture and pigmentation and the visible reduction of wrinkles and fine lines with glycolic acid.

Exfoliation: Glycolic acid is a powerful exfoliant. It dissolves the bonds between dead skin cells on the skin’s surface, facilitating their removal and revealing newer, healthier skin underneath.
Increased Collagen Production: It stimulates collagen production, which is essential for skin elasticity and firmness. This action helps reduce the appearance of fine lines and wrinkles.
Enhanced Skin Hydration: Glycolic acid improves the skin's ability to retain moisture, enhancing hydration and a more plump, vibrant skin appearance.
Skin Brightening: Removing dead skin cells can brighten the complexion and reduce the appearance of dark spots and hyperpigmentation.
Improved Skin Texture: Regular use of glycolic acid can lead to smoother, more even textured skin, making it beneficial for conditions like keratosis pilaris.
Acne Treatment: Its exfoliating properties help in unclogging pores, thereby reducing the occurrence of acne breakouts.

Aging Skin: Glycolic acid is widely used in anti-aging products to reduce signs of aging, such as fine lines, wrinkles, and age spots.
Acne-Prone Skin: It helps manage acne by exfoliating the skin and removing blockage from pores.
Hyperpigmentation: It effectively treats hyperpigmentation by accelerating the removal of hyperpigmented skin cells.
Textural Irregularities: Glycolic acid can improve skin texture and is beneficial for treating keratosis pilaris and other conditions of rough skin.
Sun-Damaged Skin: It helps rejuvenate sun-damaged skin by accelerating cell turnover and collagen synthesis.

Bernstein, E. F. (2001). Glycolic acid treatment increases type I collagen mRNA and hyaluronic acid content of human skin. Dermatologic Surgery.
Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology.
Sharad, J. (2013). Glycolic acid peel therapy – a current review. Clinical, Cosmetic and Investigational Dermatology.
Smith, W. P. (1996). Epidermal and dermal effects of topical lactic acid. Journal of the American Academy of Dermatology, 35(3), 388-391.

Full ingredient list

Aqua, Propylene glycol, Glycolic acid, Glycerin, Polyacrylamide & C13-14 Isoparaffin & Laureth-7, Triethanolamine, Hydroxyethylcellulose, Potassium hydroxide

Glycolic Gel: Trial

R 124.35

Glycolic Gel: Trial

product benefits

Improve Sun-Damaged Skin

Reduce visible signs of sun damage like hyperpigmentation, uneven skin tone, and textural irregularities.

Boost Collagen Production

Restore skin structure by stimulating fibroblast activity and supporting the synthesis of new collagen fibers, improving skin firmness and elasticity.

Refine Skin Texture & Pores

Promote healthy skin cell regeneration and optimize the skin's structural integrity to refine skin texture and diminish pore size, resulting in a more even, smooth, and polished look.

Enhance skin renewal

Enhance the skin's renewal process, replacing older, damaged cells with newer, healthier ones. The proliferation of new skin cells refines the skin's surface, diminishes signs of aging, and improves overall skin clarity.

glycolic gel

mode of action

Pigmentation Treatment

Inducing chemical exfoliation removes dead, damaged, and discolored skin cells faster from post-inflammatory hyperpigmentation. It drives new skin cells to the surface of the face. This spurred cell renewal helps reveal the healthier, underlying skin and promotes a more even skin tone overall.
Glycolic acid suppresses melanin formation by inhibiting tyrosinase activity.

Anti-aging

Exfoliate dead skin cells and reveal the newer, brighter layers underneath by acting on the stratum corneum (the outermost layer of skin). Normal, intact stratum corneum consists of tightly packed layers of tightly bonded dead skin cells. Glycolic acid loosens these bonds. With their glue dissolved by glycolic acid, those tough, rough layers of dead skin cells can more easily slough away.
The small molecular size of Glycolic acid allows for deeper penetration in the skin layers, where it stimulates fibroblasts to produce increased amounts of collagen. By stimulating collagen production, it helps skin feel firmer and minimises fine lines and wrinkles.

Exfoliating

Glycolic acid facilitates progressive weakening of cohesion of the intercellular material of the outermost layers of the skin (stratum corneum), resulting in uniform exfoliation.
Disrupts cellular junctions to exfoliate dead skin cells.

Microbial Control

Glycolic acid exhibits pH-dependent antibacterial activity against C. acnes. At a pH of 3-3.5, Glycolic acid kills C. acnes cells by disrupting bacterial cell membranes.

Anti-Inflammatory & Anti-Acne

Exhibits pH-dependent antibacterial activity by disrupting C. acnes cell membranes at a low pH (3-3.5), effectively killing acne-causing bacteria.
Exfoliates dead skin cells, preventing pore blockages and reducing the risk of breakouts.
Minimizes redness and swelling by limiting bacterial-triggered inflammatory responses.
Reduces acne-related inflammation by addressing both bacterial activity and clogged pores.

indications for Glycolic Gel: Trial

Dull & Lifeless Skin
Pigmentation
Rough Skin Texture
Aging Skin
Volume loss
Enlarged Pores

Exfoliating treatment that removes dead skin cells, brightens skin tone, stimulates collagen production, improves texture, and enhances hydration.

glycolic acid

exfoliating & renewing action

Dead skin cells accumulate on the surface, making the skin appear dull and uneven. Glycolic acid dissolves the bonds holding dead skin cells together, promoting their removal. This exfoliation reveals brighter, smoother skin and improves texture while stimulating collagen for a firmer, more youthful appearance.

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