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Article: Keratosis Pilaris

Keratosis Pilaris

If you have rough, sandpaper-like bumps on the backs of your arms or legs or other areas of your body, you may have keratosis pilaris or KP. While harmless, KP bumps can be unsightly and annoying and can be a long-term skin problem for both men and women. Luckily, there are some things you can do to get rid of KP bumps and maintain smooth, healthy-looking skin year-round.


kp-what

What is Keratosis Pilaris?

Keratosis pilaris is a common skin condition that causes small, rough bumps to form. These bumps can be red or the same color as the rest of your skin tone, and they do not usually hurt or itch (except if your skin is dry).

Often confused with tiny goosebumps or acne, keratosis pilaris occurs when a skin-based protein [keratin] forms hard plugs within hair follicles.  The result is skin-colored bumps about the size of a grain of sand and a fine, bumpy texture. Some cases are accompanied by redness.

Keratin is an essential protein in your hair, skin, and nails. However, when too much keratin is produced, it can form small, scaly bumps on your skin. People with dry skin tend to be more susceptible to keratosis pilaris since dry skin flakes can become trapped inside pores, causing debris buildup and excess keratin within hair follicles.

Keratosis pilaris is found most commonly on the back and outer sides of the upper arms (though the lower arms can also be affected).  It can also be found on the thighs, hands, and the tops of the legs, flanks, buttocks, and face, where it is commonly mistaken for acne (especially in adolescents).

Keratosis pilaris also appears to be linked with atopic dermatitis or eczema. Like eczema, KP bumps may go away independently as a child grows into adulthood. For others, KP bumps can be a long-term skin concern.


kp-types

Types of Keratosis Pilaris

  • Keratosis pilaris rubra (red, inflamed bumps that can be on arms, head, and legs)
  • Keratosis pilaris alba (rough, bumpy skin with no irritation)
  • Keratosis pilaris rubra faceii (reddish rash on the cheeks)

treating-kp

How Do I Get Rid of KP Bumps?

The best way to get to the root of the problem is to use a leave-on exfoliant containing salicylic acid (BHA). BHA is an excellent multi­tasking ingredient because it gets beyond the skin’s surface to exfoliate inside the pore, removing the hard clog that causes the problem. The clog is gone, and the problem is relieved!

Glycolic acid can lower the pH of the skin and, therefore, loosen the “glue” that holds skin cells together. This allows dead skin and debris flakes to detach from the fresh new cells underneath.

Moisturize with a barrier repair cream. Dry, dehydrated skin worsens KP bumps, so use a barrier repair moisturizer to strengthen the skin barrier and reduce dryness and dehydration.


prevent-kp

Are KP Bumps Preventable?

Because KP bumps are caused by genetics, they cannot always be entirely prevented. However, you can reduce their appearance and the likelihood that they will show up on your skin again by keeping your skin moisturized and exfoliating several times throughout the week.

dermexcel products for

keratosis pilaris

repair & renew

repair & renew

Chemical Peel Spray Chemical Peel Spray Chemical Peel Spray Chemical Peel Spray
Sale priceR 621.74

SIZE: 50 mL

Exfoliating

Exfoliating

Smooth Skin

Smooth Skin

Ingrown hair

Ingrown hair

Anti-Acne

Anti-Acne

Anti-Aging

Anti-Aging


A scientifically-formulated solution, leveraging the synergistic effects of 10% Glycolic acid and 3% Salicylic acid. These active ingredients are renowned in the medical and pharmaceutical fields for their potent anti-aging and anti-acne properties.

Salicylic acid, a beta hydroxy acid, deeply penetrates pores, effectively targeting pimples, blackheads, keratosis pilaris, and ingrown hair bumps. It works by dissolving excess sebum and dead skin cells, thereby preventing pore clogging.

Glycolic acid, an alpha hydroxy acid, stimulates cellular turnover, aiding in the reduction of pigmentation and enhancing collagen production, which is crucial for maintaining skin elasticity and reducing signs of aging.

The product is designed as a lightweight liquid that dries rapidly on the skin, eliminating concerns about staining fabrics. This makes it a practical and efficient solution for combating body acne, including on the back and buttocks, and for promoting overall skin health.


Salicylic Acid

Salicylic acid, a renowned beta hydroxy acid (BHA), is a cornerstone in dermatology and skincare due to its exceptional keratolytic and comedolytic properties. Its unique ability to penetrate oil-laden hair follicle pores makes it particularly effective in treating acne-prone and oily skin types.

Salicylic acid dissolves skin debris (sebum and dead skin cells) that clogs pores and causes acne. It's a mild antibacterial and powerful anti-inflammatory agent that helps reduce the redness and swelling associated with breakouts.

What sets salicylic acid apart in dermatological treatments is its ability to exfoliate the skin, not just on the surface but within the pores themselves. This is due to its oil-soluble nature, which allows it to penetrate deep into the pores and dissolve the keratin plugs that lead to blackheads and whiteheads.

Furthermore, salicylic acid also has the capacity to adjust the pH of the skin, creating an environment less favorable for the growth of acne-causing bacteria. Salicylic acid's efficacy in treating various skin conditions, particularly acne, has been extensively documented in the scientific literature. Studies have consistently shown its ability to reduce acne lesions in terms of count and severity. Additionally, salicylic acid is highly recommended for its effectiveness in treating other skin conditions, such as psoriasis and dandruff, due to its ability to soften and remove scales and flakes from the skin.


Physiological Effects

  • Keratolytic Action: Salicylic acid is known for its ability to exfoliate the skin by dissolving the intercellular 'glue' that holds skin cells together, helping to remove dead skin cells and unclog pores.
  • Comedolytic Effect: It is particularly effective in reducing comedones (blackheads and whiteheads) by unclogging pores and preventing the formation of new comedones.
  • Anti-inflammatory Properties: Salicylic acid reduces inflammation, which is beneficial in treating acne and other inflammatory skin conditions.
  • Sebum Regulation: It helps to regulate oil production, making it a valuable ingredient for managing oily and acne-prone skin.
  • Penetration Enhancement: Due to its lipophilic nature, it can penetrate sebum-filled follicles, effectively treating acne located deep within the pores.

Role in Managing Dermatological Conditions

  • Acne Vulgaris: Salicylic acid is a cornerstone in acne treatment, effectively preventing and treating existing acne lesions.
  • Psoriasis: Its keratolytic properties make it helpful in softening and removing scales associated with psoriasis.
  • Warts: Salicylic acid is commonly used to treat warts because it can exfoliate and remove thick skin.
  • Seborrheic Dermatitis: It helps manage seborrheic dermatitis by reducing scaling and redness.
  • Keratosis Pilaris: Salicylic acid can aid in smoothing the rough bumps associated with keratosis pilaris.

References

  • Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., & Thiboutot, D. M. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973.e33.
  • Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, cosmetic and investigational dermatology, 3, 135.
  • Zander, E., & Weisman, S. (1992). Treatment of acne vulgaris with salicylic acid pads. Clinical Therapeutics.
  • Gupta, A. K., & Nicol, K. (2004). The use of sulfur in dermatology. Journal of Drugs in Dermatology.
Glycolic acid

Glycolic acid is highly acclaimed for its remarkable exfoliating and rejuvenating properties. Its small molecular size enables deep skin penetration, fostering efficient exfoliation at the cellular level.

Glycolic acid’s water solubility allows it to penetrate the upper layers of the skin easily. Its primary mechanism of action involves weakening the bonds between dead skin cells, promoting their shedding, and revealing the newer, healthier skin beneath. This process of accelerated cell turnover is instrumental in addressing a range of skin concerns, from aging signs like fine lines and wrinkles to texture irregularities and hyperpigmentation.

Glycolic acid's efficacy extends beyond mere exfoliation. It's also recognized for stimulating collagen production, a crucial protein in maintaining skin's elasticity and firmness. This aspect contributes to its anti-aging benefits. Furthermore, its hydrating properties add to its appeal, as they help increase the skin's capacity to retain moisture, leading to a more supple and vibrant complexion.

Clinical studies have consistently supported glycolic acid's role in improving skin appearance. Research indicates significant improvements in skin texture and pigmentation and the visible reduction of wrinkles and fine lines with glycolic acid.


Physiological Effects

  • Exfoliation: Glycolic acid is a powerful exfoliant. It dissolves the bonds between dead skin cells on the skin’s surface, facilitating their removal and revealing newer, healthier skin underneath.
  • Increased Collagen Production: It stimulates collagen production, which is essential for skin elasticity and firmness. This action helps reduce the appearance of fine lines and wrinkles.
  • Enhanced Skin Hydration: Glycolic acid improves the skin's ability to retain moisture, enhancing hydration and a more plump, vibrant skin appearance.
  • Skin Brightening: Removing dead skin cells can brighten the complexion and reduce the appearance of dark spots and hyperpigmentation.
  • Improved Skin Texture: Regular use of glycolic acid can lead to smoother, more even textured skin, making it beneficial for conditions like keratosis pilaris.
  • Acne Treatment: Its exfoliating properties help in unclogging pores, thereby reducing the occurrence of acne breakouts.

Role in Managing Dermatological Conditions

  • Aging Skin: Glycolic acid is widely used in anti-aging products to reduce signs of aging, such as fine lines, wrinkles, and age spots.
  • Acne-Prone Skin: It helps manage acne by exfoliating the skin and removing blockage from pores.
  • Hyperpigmentation: It effectively treats hyperpigmentation by accelerating the removal of hyperpigmented skin cells.
  • Textural Irregularities: Glycolic acid can improve skin texture and is beneficial for treating keratosis pilaris and other conditions of rough skin.
  • Sun-Damaged Skin: It helps rejuvenate sun-damaged skin by accelerating cell turnover and collagen synthesis.

References

  • Bernstein, E. F. (2001). Glycolic acid treatment increases type I collagen mRNA and hyaluronic acid content of human skin. Dermatologic Surgery.
  • Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology.
  • Sharad, J. (2013). Glycolic acid peel therapy – a current review. Clinical, Cosmetic and Investigational Dermatology.
  • Smith, W. P. (1996). Epidermal and dermal effects of topical lactic acid. Journal of the American Academy of Dermatology, 35(3), 388-391.

repair & renew

repair & renew

Dermalytic Dermalytic Dermalytic Dermalytic
Sale priceR 265.22
Size:

Size

Ingrown hair

Ingrown hair

Body Acne

Body Acne

Keratosis Pilaris

Keratosis Pilaris

Rough Skin

Rough Skin

cracked heels

cracked heels


A clinically-formulated ointment to treat calloused, rough, and dry skin. It's more than a standard moisturizer; it exfoliates dead skin cells and replenishes moisture. The product creates an optimal environment for skin health, leading to a smoother complexion. Key ingredients include 10% Glycolic acid for exfoliation, 10% Lactic acid for removing dead cells, and 20% Urea for lasting hydration. Its "cream-ointment" base balances efficacy and application comfort. Dermalytic's medical-grade formula and scientific skincare approach visibly improve skin texture, giving users a renewed sense of confidence and comfort.


Glycolic Acid

Glycolic acid is highly acclaimed for its remarkable exfoliating and rejuvenating properties. Its small molecular size enables deep skin penetration, fostering efficient exfoliation at the cellular level.

Glycolic acid’s water solubility allows it to penetrate the upper layers of the skin easily. Its primary mechanism of action involves weakening the bonds between dead skin cells, promoting their shedding, and revealing the newer, healthier skin beneath. This process of accelerated cell turnover is instrumental in addressing a range of skin concerns, from aging signs like fine lines and wrinkles to texture irregularities and hyperpigmentation.

Glycolic acid's efficacy extends beyond mere exfoliation. It's also recognized for stimulating collagen production, a crucial protein in maintaining skin's elasticity and firmness. This aspect contributes to its anti-aging benefits. Furthermore, its hydrating properties add to its appeal, as they help increase the skin's capacity to retain moisture, leading to a more supple and vibrant complexion.

Clinical studies have consistently supported glycolic acid's role in improving skin appearance. Research indicates significant improvements in skin texture and pigmentation and the visible reduction of wrinkles and fine lines with glycolic acid.


Physiological Effects

  • Exfoliation: Glycolic acid is a powerful exfoliant. It dissolves the bonds between dead skin cells on the skin’s surface, facilitating their removal and revealing newer, healthier skin underneath.
  • Increased Collagen Production: It stimulates collagen production, which is essential for skin elasticity and firmness. This action helps reduce the appearance of fine lines and wrinkles.
  • Enhanced Skin Hydration: Glycolic acid improves the skin's ability to retain moisture, enhancing hydration and a more plump, vibrant skin appearance.
  • Skin Brightening: Removing dead skin cells can brighten the complexion and reduce the appearance of dark spots and hyperpigmentation.
  • Improved Skin Texture: Regular use of glycolic acid can lead to smoother, more even textured skin, making it beneficial for conditions like keratosis pilaris.
  • Acne Treatment: Its exfoliating properties help in unclogging pores, thereby reducing the occurrence of acne breakouts.

Role in Managing Dermatological Conditions

  • Aging Skin: Glycolic acid is widely used in anti-aging products to reduce signs of aging, such as fine lines, wrinkles, and age spots.
  • Acne-Prone Skin: It helps manage acne by exfoliating the skin and removing blockage from pores.
  • Hyperpigmentation: It effectively treats hyperpigmentation by accelerating the removal of hyperpigmented skin cells.
  • Textural Irregularities: Glycolic acid can improve skin texture and is beneficial for treating keratosis pilaris and other conditions of rough skin.
  • Sun-Damaged Skin: It helps rejuvenate sun-damaged skin by accelerating cell turnover and collagen synthesis.

References

  • Bernstein, E. F. (2001). Glycolic acid treatment increases type I collagen mRNA and hyaluronic acid content of human skin. Dermatologic Surgery.
  • Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology.
  • Sharad, J. (2013). Glycolic acid peel therapy – a current review. Clinical, Cosmetic and Investigational Dermatology.
  • Smith, W. P. (1996). Epidermal and dermal effects of topical lactic acid. Journal of the American Academy of Dermatology, 35(3), 388-391.
Urea

Urea, a naturally occurring compound in the skin, is widely recognized in dermatology and skin care for its hydrating and keratolytic properties. It is a component of the skin's natural moisturizing factor (NMF) and is crucial in maintaining skin hydration and barrier function.

In skin care, urea is valued for its dual action: it acts as a humectant, drawing moisture into the skin, and as a keratolytic agent, helping to break down the protein bonds between dead skin cells, leading to smoother and softer skin. This makes it particularly effective in treating dry, rough, and scaly skin conditions such as eczema, psoriasis, and ichthyosis.

Additionally, urea has been shown to have antimicrobial properties and can aid in skin barrier repair, further underscoring its utility in treating various skin conditions.


Physiological Effects

  • Hydration: Urea is a potent humectant, meaning it draws moisture into the skin, significantly improving hydration and maintaining skin moisture balance.
  • Keratolytic Action: Urea has keratolytic properties, helping to break down the bonds between dead skin cells and aiding in the exfoliation of the skin's surface.
  • Skin Barrier Function: Urea enhances the skin's barrier function, helping to prevent moisture loss and protect the skin from external irritants.
  • Soothing Effect: It soothes dry, itchy, and irritated skin, providing relief from various skin conditions.

Role in Managing Dermatological Conditions

  • Dry Skin (Xerosis): Urea is a key ingredient in many moisturizers for treating dry skin due to its excellent hydrating properties.
  • Eczema and Psoriasis: It helps manage symptoms like dryness, scaling, and itching in eczema and psoriasis.
  • Ichthyosis and Keratosis Pilaris: The keratolytic action of urea makes it effective in conditions characterized by excessive skin scaling, such as ichthyosis and keratosis pilaris.
  • Cracked Heels and Calluses: Urea-based creams effectively soften and reduce thickened skin on heels and calluses.
  • Aging Skin: It can improve skin texture and hydration in aging skin.

References

  • Lodén, M. (2003). Role of topical emollients and moisturizers in the treatment of dry skin barrier disorders. American Journal of Clinical Dermatology.
  • Pan, M., et al. (2013). Efficacy of topical urea in the treatment of xerosis. American Journal of Clinical Dermatology.
  • Fluhr, J. W., et al. (2008). Glycerol and the skin: holistic approach to its origin and functions. British Journal of Dermatology.
  • Grether-Beck, S., Felsner, I., Brenden, H., Kohne, Z., Majora, M., Marini, A., ... & Krutmann, J. (2012). Urea uptake enhances barrier function and antimicrobial defense in humans by regulating epidermal gene expression. Journal of Investigative Dermatology, 132(6), 1561-1572.
Lactic acid

Lactic acid, a member of the alpha hydroxy acid (AHA) family, is a well-regarded ingredient in the field of dermatology and skincare for its exfoliating and moisturizing properties. Naturally occurring in sour milk and other fermented products, lactic acid is also produced in the human body and plays a role in various metabolic processes.

In skincare, lactic acid is primarily known for its ability to exfoliate the skin gently. By breaking down the bonds that hold dead skin cells together on the skin's surface, lactic acid helps to promote the shedding of these cells, revealing fresher, brighter skin underneath. This exfoliation process improves skin texture and tone and stimulates cell renewal.

One key advantage of lactic acid over other AHAs is its moisturizing capability. Lactic acid helps increase the skin's natural moisturizing factors (NMF), essential for keeping the skin hydrated. Its unique ability to draw moisture into the skin is particularly beneficial for treating dry and dehydrated skin conditions.


Physiological Effects

  • Exfoliation: A gentle exfoliant that removes dead skin cells from the skin's surface, promoting smooth skin.
  • Moisture Retention: It is a humectant that helps the skin retain moisture, improving hydration and reducing dryness.
  • Collagen Stimulation: Lactic acid can stimulate collagen production in the deeper layers of the skin, aiding in skin firmness and reducing the appearance of fine lines and wrinkles.
  • Skin Brightening: It helps lighten dark spots and even out skin tone, effectively treating hyperpigmentation.
  • pH Balancing: Lactic acid can help balance the skin's natural pH levels, which is beneficial for maintaining a healthy skin barrier.

Role in Managing Dermatological Conditions

  • Aging Skin: Lactic acid's collagen-stimulating and exfoliating properties make it effective in anti-aging treatments, reducing signs of aging like wrinkles and age spots.
  • Acne-Prone Skin: By unclogging pores and removing dead skin cells, lactic acid can help reduce acne breakouts.
  • Dry Skin (Xerosis): Its humectant properties are beneficial in hydrating and relieving dry skin.
  • Hyperpigmentation: Lactic acid treats hyperpigmentation issues, including melasma and sun damage.
  • Keratosis Pilaris: It can help manage keratosis pilaris by exfoliating the excess keratin that blocks hair follicles.

References

  • Smith, W. P. (1996). Epidermal and dermal effects of topical lactic acid. Journal of the American Academy of Dermatology.
  • Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology.
  • Stiller, M. J., et al. (1996). Topical 8% glycolic acid and 8% L-lactic acid creams for the treatment of photodamaged skin. A double-blind vehicle-controlled clinical trial. Archives of Dermatology.
  • Rawlings, A. V., Davies, A., Carlomusto, M., Pillai, S., Zhang, K., Kosturko, R., ... & Watson, D. (1996). Effect of lactic acid isomers on keratinocyte ceramide synthesis, stratum corneum lipid levels and stratum corneum barrier function. Archives of Dermatological Research, 288(7), 383-390.

repair & renew

repair & renew

Excelerate Excelerate Excelerate Excelerate
Sale priceR 175.65
Size:

Size

Strength:

Strength

↓ Sebum

↓ Sebum

Unclog Pores

Unclog Pores

Ingrown hair

Ingrown hair

Anti-Acne

Anti-Acne

↓ inflammation

↓ inflammation


A high-potency salicylic acid treatment available in two strengths – 15% and 30%. This efficacious formulation is designed to systematically counteract acne formation by addressing the critical stages of acne development: comedones, bacteria, and inflammation. Its unique keratolytic action accelerates the turnover of skin cells, fostering flaking on the epidermis and inside the pores. This process aids in unclogging pores, a fundamental step in acne management.

Excelerate also maintains a balance in oil secretion, an essential aspect of skin health. By targeting these key factors, Excelerate is an effective solution for comprehensive acne care, contributing to improved skin clarity and texture. It should be used under the guidance of a healthcare provider.


Salicylic Acid | 15%

Salicylic acid, a renowned beta hydroxy acid (BHA), is a cornerstone in dermatology and skincare due to its exceptional keratolytic and comedolytic properties. Its unique ability to penetrate oil-laden hair follicle pores makes it particularly effective in treating acne-prone and oily skin types.

Salicylic acid dissolves skin debris (sebum and dead skin cells) that clogs pores and causes acne. It's a mild antibacterial and powerful anti-inflammatory agent that helps reduce the redness and swelling associated with breakouts.

What sets salicylic acid apart in dermatological treatments is its ability to exfoliate the skin, not just on the surface but within the pores themselves. This is due to its oil-soluble nature, which allows it to penetrate deep into the pores and dissolve the keratin plugs that lead to blackheads and whiteheads.

Furthermore, salicylic acid also has the capacity to adjust the pH of the skin, creating an environment less favorable for the growth of acne-causing bacteria. Salicylic acid's efficacy in treating various skin conditions, particularly acne, has been extensively documented in the scientific literature. Studies have consistently shown its ability to reduce acne lesions in terms of count and severity. Additionally, salicylic acid is highly recommended for its effectiveness in treating other skin conditions, such as psoriasis and dandruff, due to its ability to soften and remove scales and flakes from the skin.


Physiological Effects

  • Keratolytic Action: Salicylic acid is known for its ability to exfoliate the skin by dissolving the intercellular 'glue' that holds skin cells together, helping to remove dead skin cells and unclog pores.
  • Comedolytic Effect: It is particularly effective in reducing comedones (blackheads and whiteheads) by unclogging pores and preventing the formation of new comedones.
  • Anti-inflammatory Properties: Salicylic acid reduces inflammation, which is beneficial in treating acne and other inflammatory skin conditions.
  • Sebum Regulation: It helps to regulate oil production, making it a valuable ingredient for managing oily and acne-prone skin.
  • Penetration Enhancement: Due to its lipophilic nature, it can penetrate sebum-filled follicles, effectively treating acne located deep within the pores.

Role in Managing Dermatological Conditions

  • Acne Vulgaris: Salicylic acid is a cornerstone in acne treatment, effectively preventing and treating existing acne lesions.
  • Psoriasis: Its keratolytic properties make it helpful in softening and removing scales associated with psoriasis.
  • Warts: Salicylic acid is commonly used to treat warts because it can exfoliate and remove thick skin.
  • Seborrheic Dermatitis: It helps manage seborrheic dermatitis by reducing scaling and redness.
  • Keratosis Pilaris: Salicylic acid can aid in smoothing the rough bumps associated with keratosis pilaris.

References

  • Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., & Thiboutot, D. M. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973.e33.
  • Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, cosmetic and investigational dermatology, 3, 135.
  • Zander, E., & Weisman, S. (1992). Treatment of acne vulgaris with salicylic acid pads. Clinical Therapeutics.
  • Gupta, A. K., & Nicol, K. (2004). The use of sulfur in dermatology. Journal of Drugs in Dermatology.
Salicylic Acid | 30%

Salicylic acid, a renowned beta hydroxy acid (BHA), is a cornerstone in dermatology and skincare due to its exceptional keratolytic and comedolytic properties. Its unique ability to penetrate oil-laden hair follicle pores makes it particularly effective in treating acne-prone and oily skin types.

Salicylic acid dissolves skin debris (sebum and dead skin cells) that clogs pores and causes acne. It's a mild antibacterial and powerful anti-inflammatory agent that helps reduce the redness and swelling associated with breakouts.

What sets salicylic acid apart in dermatological treatments is its ability to exfoliate the skin, not just on the surface but within the pores themselves. This is due to its oil-soluble nature, which allows it to penetrate deep into the pores and dissolve the keratin plugs that lead to blackheads and whiteheads.

Furthermore, salicylic acid also has the capacity to adjust the pH of the skin, creating an environment less favorable for the growth of acne-causing bacteria. Salicylic acid's efficacy in treating various skin conditions, particularly acne, has been extensively documented in the scientific literature. Studies have consistently shown its ability to reduce acne lesions in terms of count and severity. Additionally, salicylic acid is highly recommended for its effectiveness in treating other skin conditions, such as psoriasis and dandruff, due to its ability to soften and remove scales and flakes from the skin.


Physiological Effects

  • Keratolytic Action: Salicylic acid is known for its ability to exfoliate the skin by dissolving the intercellular 'glue' that holds skin cells together, helping to remove dead skin cells and unclog pores.
  • Comedolytic Effect: It is particularly effective in reducing comedones (blackheads and whiteheads) by unclogging pores and preventing the formation of new comedones.
  • Anti-inflammatory Properties: Salicylic acid reduces inflammation, which is beneficial in treating acne and other inflammatory skin conditions.
  • Sebum Regulation: It helps to regulate oil production, making it a valuable ingredient for managing oily and acne-prone skin.
  • Penetration Enhancement: Due to its lipophilic nature, it can penetrate sebum-filled follicles, effectively treating acne located deep within the pores.

Role in Managing Dermatological Conditions

  • Acne Vulgaris: Salicylic acid is a cornerstone in acne treatment, effectively preventing and treating existing acne lesions.
  • Psoriasis: Its keratolytic properties make it helpful in softening and removing scales associated with psoriasis.
  • Warts: Salicylic acid is commonly used to treat warts because it can exfoliate and remove thick skin.
  • Seborrheic Dermatitis: It helps manage seborrheic dermatitis by reducing scaling and redness.
  • Keratosis Pilaris: Salicylic acid can aid in smoothing the rough bumps associated with keratosis pilaris.

References

  • Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., & Thiboutot, D. M. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973.e33.
  • Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, cosmetic and investigational dermatology, 3, 135.
  • Zander, E., & Weisman, S. (1992). Treatment of acne vulgaris with salicylic acid pads. Clinical Therapeutics.
  • Gupta, A. K., & Nicol, K. (2004). The use of sulfur in dermatology. Journal of Drugs in Dermatology.