website
Skip to content
Home
Do Your Assessment
Products per Dermal Diagnosis
What is the Dermal Diagnosis?
About Us
Contact Us / FAQ
Reviews and Testimonials
All Products
Cleansers
Treatment Serums
Exfoliators
Moisturizers
Eye Serums
Sunscreen
Treatment Packs
Body Products
Devices
Gifts
Trial Sizes
DermAdvice
Help Desk
DermRewards
DermExcel™ Practice Locator
  • Account
Cart

Your cart is empty

  • HomeHome
  • Dermal Diagnosis
    • Do Your Assessment
    • Products per Dermal Diagnosis
    • What is the Dermal Diagnosis?
  • About Us
    • About Us
    • Contact Us / FAQ
    • Reviews and Testimonials
  • Products
    • All Products
    • Cleansers
    • Treatment Serums
    • Exfoliators
    • Moisturizers
    • Eye Serums
    • Sunscreen
    • Treatment Packs
    • Body Products
    • Devices
    • Gifts
    • Trial Sizes
  • Resources
    • DermAdvice
    • Help Desk
    • DermRewards
    • DermExcel™ Practice Locator
Dermalhealthstore™
Access Denied
IMPORTANT! If you’re a store owner, please make sure you have Customer accounts enabled in your Store Admin, as you have customer based locks set up with EasyLockdown app. Enable Customer Accounts
Dermalytic: Trial
Dermalytic: Trial
Dermalytic: Trial
Dermalytic: Trial
Dermalytic: Trial
Dermalytic: Trial
Dermalytic: Trial
Dermalytic: Trial

DermExcel™

Dermalytic: Trial

R 36.52

5ml

A powerful, medical strength moisturizing and keratolytic ointment essential for calloused, rough, and dry skin.

It exfoliates dead skin cells while restoring moisture to the new cell layer, providing an optimal environment for healthy skin.

Enhanced with active ingredients, it doesn’t just cover up dry skin. It loosens and removes the dry skin, so it’s skin softening and moisturizing ingredients can penetrate the rough skin barrier and visibly help restore healthy skin.

The specially designed base in the form of "cream-ointment" does not leave a strong greasiness.

  • Treatment of dry or cracked skin on upper legs, feet, elbows, hands, and knees.
  • Pigmentation
  • Dry skin and rough skin texture
  • Shaving bumps / Folliculitis
  • Keratosis pilaris
  • Body acne
  • Aging and sun-damaged skin

ACTIVE INGREDIENTS:

  • Glycolic acid: 10%
  • Lactic acid: 10%
  • Urea: 20%

FULL INGREDIENT LIST:

Aqua, Urea, Lactic acid, Petroleum Jelly, Cetearyl alcohol, PEG 20 Stearate, Mineral Oil, Glycerine, Lanolin, Glycolic acid, Vitamin E, Phenoxyethanol, Ethylhexylglycerin

Apply to dry, cracked, hardened, or callused sections once or twice daily. For best results apply after showering or bathing and cover the area overnight.

If sensitivity occurs, discontinue use for a few days and resume treatment every third day or as tolerated. 

IMPORTANT:
Dermalytic is too potent for facial use. Do not apply to sensitive areas.

DERMALYTIC MODE OF ACTION
  • Glycolic acid and lactic acid facilitates progressive weakening of cohesion of the intercellular material of the outermost layers of the skin (stratum corneum), resulting in uniform exfoliation.
  • Glycolic acid and lactic acid disrupts cellular junctions to exfoliate dead skin cells.
  • Urea denatures keratin by breaking their hydrogen bonds or by inducing conformational changes in their protein structure.

Urea increases moisturization with the following mechanisms of action:

  • Reduce trans-epidermal water loss
  • Increase water retention
  • Enhances the resistance of the stratum corneum against osmotic stress
  • Acts as an endogenous humectant replacing water in low humidity conditions

Urea regulates epidermal proliferation with the following mechanisms of action:

  • Decreases DNA synthesis in basal cells and prolongs the generation time of post-mitosis epidermal cells
  • Induces a reduction in cellularity

Urea enhances the skin's barrier function with the following mechanisms of action:

  • Increases the gene expression of the antimicrobial peptides, cathelicidin and β-defensin-2
  • Induces a reduction in cellularity
  • Augments mRNA and protein levels of transglutaminase-1, involucrin, loricrin and filaggrin
  • Upregulates genetic transcription involved in epidermal differentiation
  • Enhances lipid synthesis
  • Upregulates AMP (Anti-microbial peptides)
  • Glycolic acid reduce acne-related inflammation. 
  • Glycolic acid exhibit pH-dependent antibacterial activity against C. acnes. At a pH of 3-3.5, glycolic acid kills C. acnes cells by disrupting bacterial cell membranes.
  • Glycolic acid exhibit pH-dependent antibacterial activity against C. acnes. At a pH of 3-3.5, glycolic acid kills C. acnes cells by disrupting bacterial cell membranes
  • Urea increases the gene expression of antimicrobial peptide, cathelicidin and β-defensin-2
  • Exfoliate dead skin cells and reveal the newer, brighter layers underneath by acting on the stratum corneum (the outermost layer of skin). Normal, intact stratum corneum consists of tightly packed layers of dead skin cells tightly bonded together. Glycolic acid loosens these bonds. With their glue dissolved by glycolic acid, those tough, rough layers of dead skin cells can more easily slough away.
  • The small molecular size of glycolic acid allows for deeper penetration in the skin layers, where it stimulates fibroblasts to produce increased amounts of collagen. By stimulating collagen production, it helps skin feel firmer and minimises fine lines and wrinkles.
  • Inducing chemical exfoliation removes dead, damaged, and discoloured skin cells from post-inflammatory hyperpigmentation faster. It drives new skin cells to the surface of the face. This spurred cell renewal helps to reveal the healthier, underlying skin, and promotes a more even skin tone overall. 
  • Glycolic acid suppresses melanin formation by inhibiting tyrosinase activity.

BENEFITS OF DERMALYTIC

Exfoliate dead skin cells.

Increase cell turnover and smooth skin texture.

Dissolve and extract cellular debris and prevent skin cells from clumping together in pores.

Provides intense skin hydration.

INDICATIONS FOR DERMALYTIC
  • Dry skin and rough skin texture
  • Callused feet
  • Aging and sun-damaged skin
  • Hyperpigmentation
  • Keratosis pilaris
  • Shaving bumps / Ingrown hair / folliculitis
  • Body acne
REVIEWS OF OUR CHEMICAL EXFOLIATORS

Customer Reviews

Based on 399 reviews
Write a review
94%
(376)
5%
(19)
1%
(4)
0%
(0)
0%
(0)
N
Natalie Badenhorst
Great product & service

I’m in love with this products

L
Linja Allen
Glycolic

Guys, the most amazing products on the market! By far worth every penny, my skin has never looked better. A month later and I'm still seeing major improvements in tone and texture. For sure a game-changing skincare routine, these products are absolutely amazing!

L
Louise Lötter
Glycolic Gel magic

Gives my skin a wonderful glow, soft feeling after use. I recommend the product to anybody.

J
Janita Hoffman
All products

All the products that I have used are truly amazing! I have truly noticed a change in my skin and it’s such a confidence boots

E
Estelle Botha
Wonderful

Great product. Very happy with the results.

J
Jacky Pienaar

Just loooooovvvveeee you're products

123
NOT SURE WHICH PRODUCTS YOU NEED?

OUR EASY 3 STEP PROCESS

Complete your 3 min Dermal Diagnosis assessment.

start

Receive your free profile and personalised treatment plan.

start

Start with your effective & simple journey to confident skin. 

start

DERMEXCEL™

Medical-grade skin care products formulated according to pharmaceutical standards of purity, potency, and stability. All active ingredients, and the concentrations and dosing protocols in which they are used, are supported by data published in the peer-reviewed medical literature.

DermExcel™ takes an easy, effective and affordable approach to evaluating and treating the skin. Targeted treatments to improve skin conditions and maintain skin health.

Invalid password
Enter

My Account

  • DermRewards Program
  • My Store Credit
  • My Account Profile
  • Gift Card Balance

Resources

  • Help Desk
  • Contact Us
  • Policies & Procedures
  • Product Reviews
  • Social Media Reviews

Dispensing Practices

  • Dispensing Practices | Stockists
  • Medical Practice Registration

BECOME A DERMEXCELLER

Receive email updates on stuff you’ll probably want to know about, including exclusive promotions, launches, and events. Unsubscribe anytime.

Information on this website is not medical advice and is provided for educational purposes only.

FOLLOW US ON SOCIAL MEDIA

© Dermalhealthstore™ 2023
★ Judge.me Reviews

Let customers speak for us

5568 reviews
Write a review
94%
(5228)
4%
(234)
1%
(72)
0%
(11)
0%
(23)
A
Medi-Zinc Cleanser
Anneen Henze
Medi-Zinc Cleanser

I have been struggling with hormonal breakouts and since I started using this incredible cleanser, I could see a change overnight! Thank you Dermexcel for an amazing product.

D
Litaderm serum
DALEEN VAN DER WESTHUIZEN
5 Stars

I am absolutely in love with it! It feels amazing on my skin and I can see the difference. I highly recommend Litaderm, it is a must have!

J
Collagen Serum
Jenine Cloete
Amazing product!

One word… LOVE!

K
Dermal Diagnosis™ | AOP
Kayla Van der Linde

Dermal Diagnosis™ | AOP

S
Renewal Facial Cleanser
Silvia Georghiades
Great product!

My skin has not looked this good on any other product I’ve tried. Absolutely love Dermexcel’s Renewal Cleanser!

J
Inflacin serum
Joadri Matthee
Very nice

Love it!!!

123