- Dry and dehydrated skin: Provides hydration and nourishment, making the skin soft and supple.
- Aging skin: Revitalize aging skin by improving skin elasticity, reducing the appearance of fine lines and wrinkles, and strengthening the skin barrier.
- Sun-damaged skin: Soothe and repair skin affected by sun damage.
- Sensitive skin: The gentle formulation is suitable for sensitive skin, providing nourishment without causing irritation.
- Rough or uneven skin texture: Improve skin texture by providing nutrients and hydration.
- Loss of skin elasticity: The lotion supports skin's elasticity by promoting a healthy skin barrier and improving hydration levels.
- Compromised skin barrier: Strengthens and restores the skin barrier, protecting it from environmental stressors and water loss.
- Uneven skin tone: Reduce hyperpigmentation and revitalize the skin.
- Dull skin: Brighten the complexion and revive dull skin, giving it a healthy and radiant appearance.
SKIN BARRIER COMPONENTS:
- Niacinamide: Vitamin B3 that strengthens the skin's barrier function, improves skin texture, and retains moisture.
- Lipid Bilayer Technology: Forms an intelligent structural bilayer on the skin that mimics and reinforces the skin's natural lipid barrier function.
- Ceramides: Lipid molecules that are a key component of the skin barrier. They are vital in maintaining the skin's barrier function and retaining moisture.
- Cholesterol: Maintain skin barrier integrity and plays a crucial role in regulating the skin's water-holding capacity.
- Essential fatty acids: Mimic and reinforce the structure and function of the skin's lipid barrier. Help maintain skin hydration, elasticity, and barrier integrity.
These skin barrier components work together to support the skin's natural barrier function, helping to protect the skin from environmental stressors, reduce water loss, and promote overall skin health. The presence of these components in Curexema contributes to its effectiveness in addressing skin issues such as eczema, dryness, and roughness.
HUMECTANTS:
- Sodium hyaluronate: A form of hyaluronic acid, that holds a large amount of water, which helps to maintain skin hydration and plumpness.
- d-Panthenol: Provitamin B5 attracts moisture to the skin and helps to keep it hydrated while providing soothing and healing properties.
- Glycerin: A powerful humectant that attracts moisture to the skin and helps maintain hydration levels, leaving the skin feeling soft and supple.
OCCLUSIVES:
- Paraffinum liquidum: Helps to lock in moisture by forming a thin film on the skin.
- Highly refined medical-grade white soft paraffin: Forms a protective barrier on the skin's surface, sealing in moisture.
EMOLLIENTS:
- Lipid Bilayer Technology: Forms an intelligent structural bilayer on the skin that mimics and reinforces the skin's natural lipid barrier function.
- Paraffinum liquidum: Forms a thin film on the skin, providing a barrier that helps lock in moisture.
- Ethylhexyl glycerin: Skin-conditioning agent that improves the skin's softness and smoothness.
- Cetyl alcohol: A fatty alcohol that smooths and moisturizes the skin.
- Isostearate: Softens and smoothes the skin while providing a protective barrier to lock in moisture.
- Cetyl stearate: A fatty alcohol that smooths and moisturizes the skin while providing a protective barrier to lock in moisture.
- Highly refined medical-grade white soft paraffin: Forms a protective barrier on the skin's surface, sealing in moisture.
- Medilan™: Effectively softens and moisturizes the skin, improving its overall texture and relieving roughness and scaling.
FULL INGREDIENT LIST:
Aqua, white soft paraffin, extra pure lanolin, emulsifying wax, glycerin, stearic acid, paraffinum liquidum, niacinamide, cetyl alcohol, cetomacrogol, isostearyl isostearate, potassium cetyl phosphate, stearic acid, ceramides, cholesterol, ethyl hexyl glycerin and phenoxyethanol, carbomer, d-panthenol, sodium hyaluronate, C12-17 alkane, triethanolamine.
- Cleanse the skin: Gently cleanse your skin with a mild, non-irritating body wash or cleanser. We recommend Dermaplan's Cremedify.
- Gently pat your skin: Use a clean, soft towel, leaving it slightly damp. This will help your skin better absorb the moisturizer and maximize its benefits.
- Apply Hydrabase: Dispense a small amount of Hydrabase body lotion onto your fingertips or palm. The amount needed will vary depending on the size of the area you are treating.
- Massage into the skin: Gently massage the lotion into your skin using circular motions, focusing on areas with dryness, sun damage, or aging concerns.
- Frequency of use: Apply Hydrabase once or twice daily, or as needed, to maintain skin hydration, improve texture, and soothe irritation. Regular use will help promote healthier, more radiant skin.
KEY BENEFITS OF HYDRABASE™ BODY LOTION

- Deep hydration: Hydrabase is formulated with pure medical glycerin, d-Panthenol, and Hyaluronic acid, which work together to provide deep, long-lasting hydration to the skin.
- Skin barrier repair: Enriched with Ceramides, fatty acids, and Cholesterol, Hydrabase helps repair, strengthen, and restore the skin barrier, promoting better moisture retention and overall skin health.
- Anti-aging: Niacinamide in the formulation supports skin cell renewal and helps improve the appearance of aging skin by revitalizing and repairing it.
- Soothing: The gentle and nourishing ingredients in Hydrabase help soothe sensitive skin and reduce irritation, making it suitable for various skin types.
- Improved skin texture: Regular use of Hydrabase can result in a smoother, more even skin texture, as it provides the necessary nutrients and hydration to support skin health.
- Enhanced skin elasticity: Hydrabase promotes a healthy skin barrier and improves hydration levels, which supports skin elasticity, leading to more supple and youthful-looking skin.
- Sun-damaged skin repair: The lotion aids in repairing skin affected by sun damage, providing nourishment and support for better recovery.
- Suitable for daily use: Hydrabase's gentle formulation is designed for everyday use, making it an ideal addition to any skincare routine.
INDICATIONS FOR HYDRABASE™ BODY LOTION

- Dry / dehydrated skin: Provides hydration and nourishment, making the skin soft and supple.
- Aging skin: Revitalize aging skin by improving skin elasticity, reducing the appearance of fine lines and wrinkles, and strengthening the skin barrier.
- Sun-damaged skin: Soothe and repair skin affected by sun damage.
- Sensitive skin: The gentle formulation is suitable for sensitive skin, providing nourishment without causing irritation.
- Rough or uneven skin texture: Improve skin texture by providing nutrients and hydration.
- Loss of skin elasticity: The lotion supports skin's elasticity by promoting a healthy skin barrier and improving hydration levels.
- Compromised skin barrier: Strengthens and restores the skin barrier, protecting it from environmental stressors and water loss.
- Uneven skin tone: Reduce hyperpigmentation and revitalize the skin.
- Dull skin: Brighten the complexion and revive dull skin, giving it a healthy and radiant appearance.
WHAT IS DRY SKIN?
- Dry skin is characterised by the lack of moisture in the stratum corneum (SC). This is the outermost skin layer.
- Water is the major softener of the skin, and when levels are low, cracks and fissures occur.
- For the skin to appear and feel normal, the water content of the SC must be greater than 10%.
- A disruption or defect in the skin's permeability barrier, allows excessive water to be lost from within the skin into the atmosphere. Referred to as transepidermal water loss (TEWL).
- When skin becomes too dry, the outer skin layers stiffen and may develop cracks. The cracks become fissures in the skin that become irritated, inflamed, and itchy.
HYDRABASE™ BODY LOTION MODE OF ACTION

Deep Hydration
The presence of medical glycerin, d-Panthenol, and Hyaluronic acid ensures that the skin is supplied with continuous moisture, thus reducing dryness and improving overall hydration.

Skin Barrier Repair
The combination of Ceramides, fatty acids, and Cholesterol in Hydrabase reinforces and restores the skin's natural barrier, helping it retain moisture and protecting it from external irritants.

Anti-aging
Niacinamide supports skin cell renewal and collagen synthesis, which helps reduce the appearance of fine lines, wrinkles, and other visible signs of aging, resulting in a revitalized and youthful complexion.

Improved skin texture and elasticity
By supplying the skin with essential nutrients and hydration, Hydrabase supports the improvement of skin texture and elasticity, making it appear smoother and more supple.

Sun-damaged Skin Repair
Hydrabase's nourishing ingredients help to replenish and rejuvenate sun-damaged skin, promoting the skin's natural healing process and reducing the impact of sun damage.

Soothing and Calming
The gentle formulation of Hydrabase is designed to provide soothing relief to sensitive and irritated skin, reducing inflammation and promoting skin comfort.
SKIN BARRIER FUNCTION


The 2 PRIMARY FUNCTIONS OF THE skin barrier




PERMEABILITY BARRIER
Creating a barrier against electrolytes- and moisture loss (TEWL - Trans-epidermal Water loss).
This function protects the skin against becoming dry.


ANTIMICROBIAL BARRIER
Creating a barrier against the entry of unwanted micro-organisms such as allergens and irritants.
This function protects the skin against irritant dermatitis and skin infections.

PERMEABILITY BARRIER
Creating a barrier against electrolytes- and moisture loss
(TEWL - Trans-epidermal Water loss).
This function protects the skin against becoming dry.

ANTIMICROBIAL BARRIER
Creating a barrier against the entry of unwanted microorganisms such as allergens and irritants.
This function protects the skin against irritant dermatitis and skin infections.
Both of these barriers are localised primarily to the stratum corneum layer of the epidermis (the outermost layer of the skin).
When these barrier functions are impaired, the result is: DRY SKIN
When these barrier functions are impaired, the result is:
DRY SKIN
These barriers are localized primarily to the epidermis's stratum corneum layer (the skin's outermost layer).
When these barrier functions are impaired, the result is: DRY SKIN
Skin Barrier Impairment results in:
DRY SKINHYDRABASE™ MOISTURISER CLASSES MODE OF ACTION
PHYSIOLOGIC LIPID-BASED BARRIER REPAIR





- Barrier repair: Amplifies lipid production and replenishes the lamellar bilayers that are critical for normal barrier function and antimicrobial defense. It is quickly absorbed into the underlying nucleated cell layers, where they incorporate into lamellar bodies.
- Accelerated healing: Promote skin healing and regeneration, particularly in damaged or compromised skin barriers.
- Improved skin texture: Restore the skin's lipid balance, resulting in smoother, more supple skin and improved overall texture.
- Enhanced skin resilience: By reinforcing the skin's natural barrier, the triple lipid therapy increases the skin's resilience against environmental stressors, irritants, and allergens, which can exacerbate dry skin conditions.
- Reduced inflammation: Reduce inflammation associated with dry skin conditions like eczema or psoriasis, relieving redness and irritation.
Physiologically replenish the lipid bilayers that are critical for normal barrier function and antimicrobial defence.
EMOLLIENTS




- Skin barrier repair: Strengthen and restore the skin's lipid barrier, which is responsible for retaining moisture and protecting the skin from irritants, allergens, and harmful microorganisms.
- Soothing: Soothe and calm irritated skin by reducing friction and providing a smooth, protective layer on the skin. This helps alleviate symptoms such as itching, redness, and inflammation.
- Skin softening: Soften rough, dry, or scaly skin by providing hydration and promoting the natural shedding of dead skin cells. This leads to smoother, healthier-looking skin.
- Improved skin texture: By hydrating and softening the skin, emollients can improve the overall appearance and texture of the skin, making it look and feel healthier and more radiant.
The emollients in Hydrabase contribute to healthier, more comfortable skin.
HUMECTANTS





- Moisture retention: Humectants are hygroscopic, meaning they can absorb water from their surrounding environment. They draw moisture from the air and bind it to the skin, helping to keep the skin hydrated.
- Enhanced penetration: Improve the absorption of other beneficial ingredients in the Curexema formulation, enabling these ingredients to penetrate deeper into the skin and provide their intended benefits more effectively.
- Skin barrier support: By increasing the skin's hydration levels, humectants help support the skin's natural barrier function, which protects the skin from irritants, allergens, and harmful microorganisms.
- Skin plumping: As humectants increase the skin's water content, they create a plumping effect, which reduces the appearance of fine lines and wrinkles and improves the overall texture and appearance of the skin.
- Soothing: Soothe irritated or inflamed skin by providing hydration and reducing dryness, which may contribute to itching, redness, and discomfort.
The humectants in Hydrabase attract and retain moisture within the skin, supporting its overall hydration and health.
OCCLUSIVES



- Water loss prevention: Occlusives create a physical barrier on the skin's surface, preventing transepidermal water loss (TEWL). This helps to maintain hydration levels within the skin and prevent excessive dryness or dehydration.
- Skin barrier support: By sealing in moisture and reducing water loss, occlusives help support and strengthen the skin's natural barrier function, which protects the skin from external irritants, allergens, and harmful microorganisms.
- Healing promotion: Occlusives create a semi-occlusive barrier that provides an optimal environment for the skin to heal, particularly in cases of damaged or compromised skin barriers, as seen in conditions like eczema or dermatitis.
- Protection from environmental factors: The barrier created by occlusives helps shield the skin from environmental factors like harsh weather conditions, pollution, and irritants that may contribute to skin dryness or irritation.
The occlusives in Curexema form a protective barrier on the skin's surface, which helps to seal in moisture and prevent water loss.
WHICH DERMAPLAN™ MOISTURISER SHOULD I USE?

HYDRABASE™
For individuals experiencing aging, sun-damaged, or dry skin, as well as individuals seeking a daily body lotion to enhance and maintain their skin's natural moisture levels. Hydrabase is suitable for individuals looking for a deeply moisturizing and nourishing product to revitalize, soothe, and repair their skin while also improving its texture and resilience.

CUREXEMA™
For individuals struggling with eczema, dry and dehydrated skin, psoriasis, and rough and scaling skin conditions. This product is ideal for those seeking a powerful and effective solution to restore and maintain their skin's health and integrity while relieving itching, dryness, redness, and irritation.

MEDIMENT™
For individuals with severely dry and irritated skin conditions, such as redness, irritation, excessive dryness, cracking, scaling, and chapping. This water-free, lipid-replenishing ointment is ideal for clients looking to create a protective barrier on their skin while facilitating an ideal environment for healing and skin regeneration. Mediment is suitable for the entire family including infants and the elderly. It is also a fantastic ointment for baby's bum.
DERMEXCEL™ HYDRATORS & MOISTURISERS REVIEWS
TREATMENT PACKS CONTAINING LITADERM SERUM
PIGMENTATION TREATMENT PACKS
ROSACEA TREATMENT PACKS
ACNE TREATMENT PACKS
"I recommend DermExcel to all my patients. Not only is it formulated by the best pharmacologists in the industry, it's also the best value for money skin care range available" .
Dr. Y Lamberts
"DermExcel brings a whole new dimension to the science-based, medical practitioner powered skincare we recommend to our patients. It's also the skincare range I personally use every day."
Dr. C Giezing
"I see impressive results with DermExcel in my practice. My patients are amazed by the results".
Dr. N Msizi
ABOUT DERMAPLAN™

Dermaplan offers expertly formulated, scientifically proven solutions for various skin concerns. Our passion for skin health and commitment to innovation has led us to create products that address our customers' unique needs. We strive to redefine body skincare standards by developing safe, effective, and clinically tested products for those struggling with skin conditions.
Our team of experienced pharmaceutical chemists and pharmacologists collaborates to create advanced formulations that address the root causes of skin challenges, such as eczema, psoriasis, dryness, and aging.
Our comprehensive, holistic approach to skincare focuses on repairing, nourishing, and protecting the skin's natural barrier using potent, high-quality ingredients and innovative technologies. Rigorous testing and adherence to the highest industry standards ensure the safety, quality, and efficacy of our products.
Discover the Dermaplan difference and let us be your partner in skin health, guiding you towards a future of comfort, confidence, and radiance.