Appropriate skin care in acne vulgaris treated with isotretinoin (Accutane / Roaccutane) involves gentle cleansing, repair of the cutaneous barrier, and maintenance of barrier function.
A combination of salicylic acid with oral isotretinoin proved to be a good and safe option to circumvent the initial flare-up of acne that is seen with Isotretinoin therapy.
Cleansing should use a gentle salicylic acid-based cleanser, free of fragrance or harsh surfactants.
Hydrating and emollient products should be noncomedogenic, hypoallergenic, non-irritating, and non-greasy, with an aqueous base. It is highly important to use specific moisturizers that contain active ingredients of sufficient quality and concentration to protect and repair the skin. Products with hyaluronic acid, glycerin, biosaccharides and oligosaccharides.
During periods of high solar exposure - dermatitis, eczema, cheilitis, and other signs of solar sensitivity are common in photo exposed areas: mainly the face, hands, and arms. An SPF 50+ UVA/UVB solar protector should be used when exposed to sun, reapplied every 2 hrs and after swimming or sweating.
For the lips and mucous membranes, lip balms should be reapplied several times per day.