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- Treatment of dry or cracked skin on upper legs, feet, elbows, hands, and knees.
- Pigmentation
- Dry skin and rough skin texture
- Shaving bumps / Folliculitis
- Keratosis pilaris
- Body acne
- Aging and sun-damaged skin
ACTIVE INGREDIENTS:
- Glycolic acid: 10%
- Lactic acid: 10%
- Urea: 20%
ANTIOXIDANTS:
- Vitamin E
HUMECTANTS:
- Urea
- Glycerin
OCCLUSIVES:
- Medilan™
- Paraffinum liquidum
EMOLLIENTS:
- Petrolatum
- Cetearyl alcohol
- Paraffinum liquidum
NATURAL MOISTURISING FACTOR:
- Urea
FULL INGREDIENT LIST:
Aqua, Urea, Lactic acid, Petrolatum, Cetearyl alcohol, PEG 20 Stearate, Paraffinum liquidum, Glycerin, Lanolin, Glycolic acid, Vitamin E, Phenoxyethanol, Ethylhexylglycerin
AREA OF APPLICATION:
- Apply to dry, cracked, hardened, or callused areas: Heels, Elbows, and Knees. For best results on heels - apply Dermalytic at night and wear heel guards to cover the area for at least an hour or overnight.
- Apply to areas with keratosis pilaris bumps and/or ingrown hair: Upper legs, Upper arms.
- Apply to areas with body acne: Chest, Back
IMPORTANT:
- Do not apply Dermalytic on your face. Dermalytic is too potent for facial use.
- If you use Dermalytic for the above-indicated areas and also want to use it on your bikini line, be careful when applying it to the bikini-line area. Apply a minimal amount, no more than once a week. You can later increase the frequency of use on this bikini-line area as needed and tolerated by your skin.
- Always apply SPF 30 or above during the day to areas not covered by your clothes.
- Do not apply Dermalytic to open wounds.
TIME OF APPLICATION:
- Apply in the evening on cleansed skin.
FREQUENCY OF APPLICATION:
- Dry, cracked, hardened or callused Heels, Elbows, and Knees: Apply every morning and/or evening as tolerated by your skin.
- Keratosis pilaris bumps and/or ingrown hair on Upper legs and Upper arms: Start by applying two times per week. Slowly increase the frequency of use as tolerated by your skin.
- If sensitivity occurs, discontinue use for a few days and resume treatment with less frequent application applications as tolerated.
DERMALYTIC MODE OF ACTION
- Glycolic acid and lactic acid facilitate the progressive weakening of cohesion of the intercellular material of the outermost layers of the skin (stratum corneum), resulting in uniform exfoliation.
- Glycolic acid and lactic acid disrupts cellular junctions to exfoliate dead skin cells.
- Urea denatures keratin by breaking their hydrogen bonds or by inducing conformational changes in their protein structure.
Urea increases moisturization with the following mechanisms of action:
- Reduce trans-epidermal water loss
- Increase water retention
- Enhances the resistance of the stratum corneum against osmotic stress
- Acts as an endogenous humectant replacing water in low humidity conditions
Urea regulates epidermal proliferation with the following mechanisms of action:
- Decreases DNA synthesis in basal cells and prolongs the generation time of post-mitosis epidermal cells
- Induces a reduction in cellularity
Urea enhances the skin's barrier function with the following mechanisms of action:
- Increases the gene expression of the antimicrobial peptides, cathelicidin and β-defensin-2
- Induces a reduction in cellularity
- Augments mRNA and protein levels of transglutaminase-1, involucrin, loricrin and filaggrin
- Upregulates genetic transcription involved in epidermal differentiation
- Enhances lipid synthesis
- Upregulates AMP (Anti-microbial peptides)
- Glycolic acid reduce acne-related inflammation.
- Glycolic acid exhibit pH-dependent antibacterial activity against C. acnes. At a pH of 3-3.5, glycolic acid kills C. acnes cells by disrupting bacterial cell membranes.
- Glycolic acid exhibit pH-dependent antibacterial activity against C. acnes. At a pH of 3-3.5, glycolic acid kills C. acnes cells by disrupting bacterial cell membranes
- Urea increases the gene expression of antimicrobial peptide, cathelicidin and β-defensin-2
- Exfoliate dead skin cells and reveal the newer, brighter layers underneath by acting on the stratum corneum (the outermost layer of skin). Normal, intact stratum corneum consists of tightly packed layers of dead skin cells tightly bonded together. Glycolic acid loosens these bonds. With their glue dissolved by glycolic acid, those tough, rough layers of dead skin cells can more easily slough away.
- The small molecular size of glycolic acid allows for deeper penetration in the skin layers, where it stimulates fibroblasts to produce increased amounts of collagen. By stimulating collagen production, it helps skin feel firmer and minimises fine lines and wrinkles.
- Inducing chemical exfoliation removes dead, damaged, and discoloured skin cells from post-inflammatory hyperpigmentation faster. It drives new skin cells to the surface of the face. This spurred cell renewal helps to reveal the healthier, underlying skin, and promotes a more even skin tone overall.
- Glycolic acid suppresses melanin formation by inhibiting tyrosinase activity.
BENEFITS OF DERMALYTIC
Exfoliate dead skin cells.
Increase cell turnover and smooth skin texture.
Dissolve and extract cellular debris and prevent skin cells from clumping together in pores.
Provides intense skin hydration.
INDICATIONS FOR DERMALYTIC
- Dry skin and rough skin texture
- Callused feet
- Aging and sun-damaged skin
- Hyperpigmentation
- Keratosis pilaris
- Shaving bumps / Ingrown hair / folliculitis
- Body acne
REVIEWS ON DERMEXCEL CHEMICAL EXFOLIATORS
DERMEXCEL™
Medical-grade skin care products formulated according to pharmaceutical standards of purity, potency, and stability. All active ingredients, and the concentrations and dosing protocols in which they are used, are supported by data published in the peer-reviewed medical literature.
DermExcel™ takes an easy, effective and affordable approach to evaluating and treating the skin. Targeted treatments to improve skin conditions and maintain skin health.
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